Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats

Post laminectomy fibrosis in spine surgery has been responsible for a high rate of failure in a short or long term. Many of this patients develop chronic or recurrent pain after surgery of discal herniation, canal stenosis etc. Although there some doubts about the etiology of this problem, it was known that fibrosis interfere with the normal mobility of roots and spinal cord. This factor is considered as the most important aspect in the genesis of the surgical failures. To avoid postoperative fibrosis, a lot of materials of interposition between posterior spine muscles and dura mater were studied, without good response. This paper studied comparatively post laminectomy fibrosis in Wistar rats with the addition of the following materials to avoid it: control group (without interposition) and expanded inert polytetrafluoroethylene membrane (Preclude Spinal Membrane®). It was observed that accurate surgical technique apparently is an important factor to prevent the formation of abundant scar tissue and that the expanded inert polytetrafluoroethylene membrane is an inert material.

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Main Authors: Barros Filho,Tarcísio Eloy Pessoa, Oliveira,Cláudia Regina G. C. M., Oliveira,Reginaldo Perilo de, Barros,Erika Meirelles Kalil Pessoa de, Marcon,Raphael Martus, Cristante,Alexandre Fogaça
Format: Digital revista
Language:English
Published: ATHA EDITORA 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522003000200007
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spelling oai:scielo:S1413-785220030002000072003-06-03Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar ratsBarros Filho,Tarcísio Eloy PessoaOliveira,Cláudia Regina G. C. M.Oliveira,Reginaldo Perilo deBarros,Erika Meirelles Kalil Pessoa deMarcon,Raphael MartusCristante,Alexandre Fogaça Laminectomy Fibrosis Wistar rats expanded inert Polytetrafluoroethylene membrane Post laminectomy fibrosis in spine surgery has been responsible for a high rate of failure in a short or long term. Many of this patients develop chronic or recurrent pain after surgery of discal herniation, canal stenosis etc. Although there some doubts about the etiology of this problem, it was known that fibrosis interfere with the normal mobility of roots and spinal cord. This factor is considered as the most important aspect in the genesis of the surgical failures. To avoid postoperative fibrosis, a lot of materials of interposition between posterior spine muscles and dura mater were studied, without good response. This paper studied comparatively post laminectomy fibrosis in Wistar rats with the addition of the following materials to avoid it: control group (without interposition) and expanded inert polytetrafluoroethylene membrane (Preclude Spinal Membrane®). It was observed that accurate surgical technique apparently is an important factor to prevent the formation of abundant scar tissue and that the expanded inert polytetrafluoroethylene membrane is an inert material.info:eu-repo/semantics/openAccessATHA EDITORAActa Ortopédica Brasileira v.11 n.2 20032003-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522003000200007en10.1590/S1413-78522003000200007
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libraryname SciELO
language English
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author Barros Filho,Tarcísio Eloy Pessoa
Oliveira,Cláudia Regina G. C. M.
Oliveira,Reginaldo Perilo de
Barros,Erika Meirelles Kalil Pessoa de
Marcon,Raphael Martus
Cristante,Alexandre Fogaça
spellingShingle Barros Filho,Tarcísio Eloy Pessoa
Oliveira,Cláudia Regina G. C. M.
Oliveira,Reginaldo Perilo de
Barros,Erika Meirelles Kalil Pessoa de
Marcon,Raphael Martus
Cristante,Alexandre Fogaça
Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
author_facet Barros Filho,Tarcísio Eloy Pessoa
Oliveira,Cláudia Regina G. C. M.
Oliveira,Reginaldo Perilo de
Barros,Erika Meirelles Kalil Pessoa de
Marcon,Raphael Martus
Cristante,Alexandre Fogaça
author_sort Barros Filho,Tarcísio Eloy Pessoa
title Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
title_short Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
title_full Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
title_fullStr Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
title_full_unstemmed Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
title_sort application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats
description Post laminectomy fibrosis in spine surgery has been responsible for a high rate of failure in a short or long term. Many of this patients develop chronic or recurrent pain after surgery of discal herniation, canal stenosis etc. Although there some doubts about the etiology of this problem, it was known that fibrosis interfere with the normal mobility of roots and spinal cord. This factor is considered as the most important aspect in the genesis of the surgical failures. To avoid postoperative fibrosis, a lot of materials of interposition between posterior spine muscles and dura mater were studied, without good response. This paper studied comparatively post laminectomy fibrosis in Wistar rats with the addition of the following materials to avoid it: control group (without interposition) and expanded inert polytetrafluoroethylene membrane (Preclude Spinal Membrane®). It was observed that accurate surgical technique apparently is an important factor to prevent the formation of abundant scar tissue and that the expanded inert polytetrafluoroethylene membrane is an inert material.
publisher ATHA EDITORA
publishDate 2003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522003000200007
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