Liver disease due to schistosoma guineensis: a review
Based on the case of a patient from the island of São Tomé who presented with intestinal and liver disease with portal hypertension due to infection with Schistosoma guineensis, the authors provide a concise review of this type of schistosomiasis, including the parasite life cycle, diagnosis, pathology, immunopathogenesis and the clinical picture of the infection, as well as posible complications and treatment. Schistosoma guineensis is geographically restricted to Central Western Africa and is the only Schistosoma species on the island of São Tomé. Usually considered to be a relatively minor disease of the lower bowel, the authors refer to four other cases on the same island that presented with serious problems, two with central system nervous disorders, one with a liver disorder and cardiopulmonary involvement, and one with liver disease and failure to thrive due to low levels of insulin growth factors IGF1 and IGF2 (formerly called somatomedins). It is important to be aware of the symptoms that may be found, so therapy can be given in time to obtain a good outcome.
| Main Authors: | , , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Portuguesa de Gastrenterologia
2006
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| Online Access: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-81782006000200006 |
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| Summary: | Based on the case of a patient from the island of São Tomé who presented with intestinal and liver disease with portal hypertension due to infection with Schistosoma guineensis, the authors provide a concise review of this type of schistosomiasis, including the parasite life cycle, diagnosis, pathology, immunopathogenesis and the clinical picture of the infection, as well as posible complications and treatment. Schistosoma guineensis is geographically restricted to Central Western Africa and is the only Schistosoma species on the island of São Tomé. Usually considered to be a relatively minor disease of the lower bowel, the authors refer to four other cases on the same island that presented with serious problems, two with central system nervous disorders, one with a liver disorder and cardiopulmonary involvement, and one with liver disease and failure to thrive due to low levels of insulin growth factors IGF1 and IGF2 (formerly called somatomedins). It is important to be aware of the symptoms that may be found, so therapy can be given in time to obtain a good outcome. |
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