Economic optimization of the number of recipients in bovine embryo transfer programs

Purchase and maintenance of recipient females account for a large proportion of the costs and determine the number of calves that can be produced in an embryo transfer program. However, the large variability of embryo production by the donors and the need to purchase and synchronize the recipients before knowing the number of embryos collected make it difficult for the decision maker to identify the ideal number of recipient females to allocate. An ex-ante evaluation to determine the optimal number of recipient females was carried out through a sensitivity analysis for the ratio between the number of recipients and donors in a simulation model. The variability for the number of embryos collected was accounted for by applying the Monte Carlo simulation technique, assuming normal distribution and known values for mean and variance. The simulation considered monthly intervals between collections, during a 24 months program. The effect of embryo freezing on the number of pregnancies was considered by introducing a stock of frozen embryos into the mathematical model. Optimal recipient/donor ratio and the cost per pregnancy were compared for three recipient synchronization protocols (prostaglandin, progesterone - P4 and Ovsynch), based on the expected performance for synchronization, conception and transfer/treated rates for each protocol. Stochastic simulation associated with sensitivity analysis was effective in identifying the optimal donor to recipient ratio. Freezing embryos is effective to reduce the operational costs per pregnancy. The estimated optimal recipient/donor ratio was 20 for prostaglandin and 16.7 for the other protocols. The P4 protocol, although the most expensive, resulted in the lowest pregnancy cost estimation followed by prostaglandin and Ovsynch.

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Main Authors: Beltrame,Renato Travassos, Barioni,Luis Gustavo, Maestri,Breno Dala, Quirino,Celia Raquel
Format: Digital revista
Language:English
Published: Escola Superior de Agricultura "Luiz de Queiroz" 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162007000300002
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spelling oai:scielo:S0103-901620070003000022007-05-25Economic optimization of the number of recipients in bovine embryo transfer programsBeltrame,Renato TravassosBarioni,Luis GustavoMaestri,Breno DalaQuirino,Celia Raquel Monte Carlo mathematical model simulation cost estimation estrus synchronization Purchase and maintenance of recipient females account for a large proportion of the costs and determine the number of calves that can be produced in an embryo transfer program. However, the large variability of embryo production by the donors and the need to purchase and synchronize the recipients before knowing the number of embryos collected make it difficult for the decision maker to identify the ideal number of recipient females to allocate. An ex-ante evaluation to determine the optimal number of recipient females was carried out through a sensitivity analysis for the ratio between the number of recipients and donors in a simulation model. The variability for the number of embryos collected was accounted for by applying the Monte Carlo simulation technique, assuming normal distribution and known values for mean and variance. The simulation considered monthly intervals between collections, during a 24 months program. The effect of embryo freezing on the number of pregnancies was considered by introducing a stock of frozen embryos into the mathematical model. Optimal recipient/donor ratio and the cost per pregnancy were compared for three recipient synchronization protocols (prostaglandin, progesterone - P4 and Ovsynch), based on the expected performance for synchronization, conception and transfer/treated rates for each protocol. Stochastic simulation associated with sensitivity analysis was effective in identifying the optimal donor to recipient ratio. Freezing embryos is effective to reduce the operational costs per pregnancy. The estimated optimal recipient/donor ratio was 20 for prostaglandin and 16.7 for the other protocols. The P4 protocol, although the most expensive, resulted in the lowest pregnancy cost estimation followed by prostaglandin and Ovsynch.info:eu-repo/semantics/openAccessEscola Superior de Agricultura "Luiz de Queiroz"Scientia Agricola v.64 n.3 20072007-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162007000300002en10.1590/S0103-90162007000300002
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collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Beltrame,Renato Travassos
Barioni,Luis Gustavo
Maestri,Breno Dala
Quirino,Celia Raquel
spellingShingle Beltrame,Renato Travassos
Barioni,Luis Gustavo
Maestri,Breno Dala
Quirino,Celia Raquel
Economic optimization of the number of recipients in bovine embryo transfer programs
author_facet Beltrame,Renato Travassos
Barioni,Luis Gustavo
Maestri,Breno Dala
Quirino,Celia Raquel
author_sort Beltrame,Renato Travassos
title Economic optimization of the number of recipients in bovine embryo transfer programs
title_short Economic optimization of the number of recipients in bovine embryo transfer programs
title_full Economic optimization of the number of recipients in bovine embryo transfer programs
title_fullStr Economic optimization of the number of recipients in bovine embryo transfer programs
title_full_unstemmed Economic optimization of the number of recipients in bovine embryo transfer programs
title_sort economic optimization of the number of recipients in bovine embryo transfer programs
description Purchase and maintenance of recipient females account for a large proportion of the costs and determine the number of calves that can be produced in an embryo transfer program. However, the large variability of embryo production by the donors and the need to purchase and synchronize the recipients before knowing the number of embryos collected make it difficult for the decision maker to identify the ideal number of recipient females to allocate. An ex-ante evaluation to determine the optimal number of recipient females was carried out through a sensitivity analysis for the ratio between the number of recipients and donors in a simulation model. The variability for the number of embryos collected was accounted for by applying the Monte Carlo simulation technique, assuming normal distribution and known values for mean and variance. The simulation considered monthly intervals between collections, during a 24 months program. The effect of embryo freezing on the number of pregnancies was considered by introducing a stock of frozen embryos into the mathematical model. Optimal recipient/donor ratio and the cost per pregnancy were compared for three recipient synchronization protocols (prostaglandin, progesterone - P4 and Ovsynch), based on the expected performance for synchronization, conception and transfer/treated rates for each protocol. Stochastic simulation associated with sensitivity analysis was effective in identifying the optimal donor to recipient ratio. Freezing embryos is effective to reduce the operational costs per pregnancy. The estimated optimal recipient/donor ratio was 20 for prostaglandin and 16.7 for the other protocols. The P4 protocol, although the most expensive, resulted in the lowest pregnancy cost estimation followed by prostaglandin and Ovsynch.
publisher Escola Superior de Agricultura "Luiz de Queiroz"
publishDate 2007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162007000300002
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