Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves
ABSTRACT: This study evaluated the effect of maternal protein supplementation during mid or late gestation on energy metabolism of the skeletal muscle of beef calves. Sixteen pregnant cows were divided into 3 groups: CTRL (not supplemented); MID (supplemented from 30 to 180 days of gestation); and LATE (supplemented from 181 to 281 days of gestation). The supplement contained 30% crude protein. Thirty days after birth, blood and muscle samples of the calves were collected for analyses of gene expression, proteins, and metabolites. No differences (P ≥ 0.15) in birth weight, performance at weaning, or muscle expression of the genes evaluated (P ≥ 0.21) were observed. Calves born to CTRL cows had a lower ratio (P = 0.03) of p-AMPK/AMPK protein in the skeletal muscle. Calves born to MID cows had lower (P = 0.04) glucose concentration than those born to LATE cows. Changes in p-AMPK/AMPK protein, indicated a possible metabolic inflexibility in the skeletal muscle of calves born to CTRL cows. These results indicated that lack of protein supplementation in pregnant cows alter the energy metabolism of their calves and reflect in a metabolic inflexibility.
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Universidade Federal de Santa Maria
2023
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oai:scielo:S0103-847820230007007012022-11-22Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calvesSanglard,Letícia Maria PereiraMarquez,David Esteban ContrerasSilva,WalmirSantos,Marta Maria dosCosta,Thaís CorreiaValente Junior,Dante TeixeiraGionbelli,Mateus PiesSerão,Nick Vergara LopesSampaio,Claudia BatistaDuarte,Marcio de Souza beef calves energy metabolism fetal programming maternal nutrition gene expression protein expression ABSTRACT: This study evaluated the effect of maternal protein supplementation during mid or late gestation on energy metabolism of the skeletal muscle of beef calves. Sixteen pregnant cows were divided into 3 groups: CTRL (not supplemented); MID (supplemented from 30 to 180 days of gestation); and LATE (supplemented from 181 to 281 days of gestation). The supplement contained 30% crude protein. Thirty days after birth, blood and muscle samples of the calves were collected for analyses of gene expression, proteins, and metabolites. No differences (P ≥ 0.15) in birth weight, performance at weaning, or muscle expression of the genes evaluated (P ≥ 0.21) were observed. Calves born to CTRL cows had a lower ratio (P = 0.03) of p-AMPK/AMPK protein in the skeletal muscle. Calves born to MID cows had lower (P = 0.04) glucose concentration than those born to LATE cows. Changes in p-AMPK/AMPK protein, indicated a possible metabolic inflexibility in the skeletal muscle of calves born to CTRL cows. These results indicated that lack of protein supplementation in pregnant cows alter the energy metabolism of their calves and reflect in a metabolic inflexibility.info:eu-repo/semantics/openAccessUniversidade Federal de Santa MariaCiência Rural v.53 n.7 20232023-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782023000700701en10.1590/0103-8478cr20210917 |
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Sanglard,Letícia Maria Pereira Marquez,David Esteban Contreras Silva,Walmir Santos,Marta Maria dos Costa,Thaís Correia Valente Junior,Dante Teixeira Gionbelli,Mateus Pies Serão,Nick Vergara Lopes Sampaio,Claudia Batista Duarte,Marcio de Souza |
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Sanglard,Letícia Maria Pereira Marquez,David Esteban Contreras Silva,Walmir Santos,Marta Maria dos Costa,Thaís Correia Valente Junior,Dante Teixeira Gionbelli,Mateus Pies Serão,Nick Vergara Lopes Sampaio,Claudia Batista Duarte,Marcio de Souza Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
author_facet |
Sanglard,Letícia Maria Pereira Marquez,David Esteban Contreras Silva,Walmir Santos,Marta Maria dos Costa,Thaís Correia Valente Junior,Dante Teixeira Gionbelli,Mateus Pies Serão,Nick Vergara Lopes Sampaio,Claudia Batista Duarte,Marcio de Souza |
author_sort |
Sanglard,Letícia Maria Pereira |
title |
Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
title_short |
Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
title_full |
Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
title_fullStr |
Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
title_full_unstemmed |
Impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
title_sort |
impact of maternal protein supplementation during mid or late gestation on skeletal muscle energy metabolism of beef calves |
description |
ABSTRACT: This study evaluated the effect of maternal protein supplementation during mid or late gestation on energy metabolism of the skeletal muscle of beef calves. Sixteen pregnant cows were divided into 3 groups: CTRL (not supplemented); MID (supplemented from 30 to 180 days of gestation); and LATE (supplemented from 181 to 281 days of gestation). The supplement contained 30% crude protein. Thirty days after birth, blood and muscle samples of the calves were collected for analyses of gene expression, proteins, and metabolites. No differences (P ≥ 0.15) in birth weight, performance at weaning, or muscle expression of the genes evaluated (P ≥ 0.21) were observed. Calves born to CTRL cows had a lower ratio (P = 0.03) of p-AMPK/AMPK protein in the skeletal muscle. Calves born to MID cows had lower (P = 0.04) glucose concentration than those born to LATE cows. Changes in p-AMPK/AMPK protein, indicated a possible metabolic inflexibility in the skeletal muscle of calves born to CTRL cows. These results indicated that lack of protein supplementation in pregnant cows alter the energy metabolism of their calves and reflect in a metabolic inflexibility. |
publisher |
Universidade Federal de Santa Maria |
publishDate |
2023 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782023000700701 |
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