Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces

There is no consensus about the clinical recommendation of the time that Duraphat® varnish should be maintained on enamel surfaces without suffering mechanical disturbance by the patient. Considering the importance of calcium fluoride (CaF2)-like reservoirs on the anticaries effect of professional fluoride application, an in vitro study was designed to test the reactivity of Duraphat® varnish with enamel forming these reservoirs as a function of time. Since most fluoride in Duraphat® varnish is insoluble to react and form products on enamel, the relative contribution of the varnish soluble and insoluble fluoride fractions to the reactivity was also evaluated. For this, whole-varnish, containing soluble and insoluble fluoride (total fluoride concentration of 23699±384 µg F/g), or centrifuged varnish, containing only soluble fluoride (fluoride concentration of 258±97 µg F/g), were applied in a standardized manner on enamel slabs (n=8/varnish group/time), which were immersed in continuously renewed artificial saliva for up to 36 h. CaF2-like reservoirs formed on enamel by varnish application were extracted using 1 M KOH and fluoride concentration was measured with ion specific electrode. The results were expressed as µg F/cm2 of enamel area. Whole varnish formed significantly higher fluoride concentration on enamel than centrifuged varnish, reaching maximum concentration at 24 h (22.0±4.5 µg F/cm2). Centrifuged varnish reached maximum concentration at 6 h (3.20±0.81 µg F/cm2). In conclusion, a longer varnish retention time than the usually recommended could improve the anticaries effect of Duraphat® varnish, allowing that NaF particles, initially insoluble in the varnish matrix, prolong the reactivity with enamel.

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Main Authors: Fernández,Constanza Estefany, Tenuta,Livia Maria Andaló, Zárate,Paulo, Cury,Jaime Aparecido
Format: Digital revista
Language:English
Published: Fundação Odontológica de Ribeirão Preto 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402014000200160
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spelling oai:scielo:S0103-644020140002001602014-08-15Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental SurfacesFernández,Constanza EstefanyTenuta,Livia Maria AndalóZárate,PauloCury,Jaime Aparecido fluorides topical fluorides calcium fluoride There is no consensus about the clinical recommendation of the time that Duraphat® varnish should be maintained on enamel surfaces without suffering mechanical disturbance by the patient. Considering the importance of calcium fluoride (CaF2)-like reservoirs on the anticaries effect of professional fluoride application, an in vitro study was designed to test the reactivity of Duraphat® varnish with enamel forming these reservoirs as a function of time. Since most fluoride in Duraphat® varnish is insoluble to react and form products on enamel, the relative contribution of the varnish soluble and insoluble fluoride fractions to the reactivity was also evaluated. For this, whole-varnish, containing soluble and insoluble fluoride (total fluoride concentration of 23699±384 µg F/g), or centrifuged varnish, containing only soluble fluoride (fluoride concentration of 258±97 µg F/g), were applied in a standardized manner on enamel slabs (n=8/varnish group/time), which were immersed in continuously renewed artificial saliva for up to 36 h. CaF2-like reservoirs formed on enamel by varnish application were extracted using 1 M KOH and fluoride concentration was measured with ion specific electrode. The results were expressed as µg F/cm2 of enamel area. Whole varnish formed significantly higher fluoride concentration on enamel than centrifuged varnish, reaching maximum concentration at 24 h (22.0±4.5 µg F/cm2). Centrifuged varnish reached maximum concentration at 6 h (3.20±0.81 µg F/cm2). In conclusion, a longer varnish retention time than the usually recommended could improve the anticaries effect of Duraphat® varnish, allowing that NaF particles, initially insoluble in the varnish matrix, prolong the reactivity with enamel.info:eu-repo/semantics/openAccessFundação Odontológica de Ribeirão PretoBrazilian Dental Journal v.25 n.2 20142014-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402014000200160en10.1590/0103-6440201302405
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countrycode BR
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libraryname SciELO
language English
format Digital
author Fernández,Constanza Estefany
Tenuta,Livia Maria Andaló
Zárate,Paulo
Cury,Jaime Aparecido
spellingShingle Fernández,Constanza Estefany
Tenuta,Livia Maria Andaló
Zárate,Paulo
Cury,Jaime Aparecido
Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces
author_facet Fernández,Constanza Estefany
Tenuta,Livia Maria Andaló
Zárate,Paulo
Cury,Jaime Aparecido
author_sort Fernández,Constanza Estefany
title Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces
title_short Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces
title_full Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces
title_fullStr Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces
title_full_unstemmed Insoluble NaF in Duraphat® May Prolong Fluoride Reactivity of Varnish Retained on Dental Surfaces
title_sort insoluble naf in duraphat® may prolong fluoride reactivity of varnish retained on dental surfaces
description There is no consensus about the clinical recommendation of the time that Duraphat® varnish should be maintained on enamel surfaces without suffering mechanical disturbance by the patient. Considering the importance of calcium fluoride (CaF2)-like reservoirs on the anticaries effect of professional fluoride application, an in vitro study was designed to test the reactivity of Duraphat® varnish with enamel forming these reservoirs as a function of time. Since most fluoride in Duraphat® varnish is insoluble to react and form products on enamel, the relative contribution of the varnish soluble and insoluble fluoride fractions to the reactivity was also evaluated. For this, whole-varnish, containing soluble and insoluble fluoride (total fluoride concentration of 23699±384 µg F/g), or centrifuged varnish, containing only soluble fluoride (fluoride concentration of 258±97 µg F/g), were applied in a standardized manner on enamel slabs (n=8/varnish group/time), which were immersed in continuously renewed artificial saliva for up to 36 h. CaF2-like reservoirs formed on enamel by varnish application were extracted using 1 M KOH and fluoride concentration was measured with ion specific electrode. The results were expressed as µg F/cm2 of enamel area. Whole varnish formed significantly higher fluoride concentration on enamel than centrifuged varnish, reaching maximum concentration at 24 h (22.0±4.5 µg F/cm2). Centrifuged varnish reached maximum concentration at 6 h (3.20±0.81 µg F/cm2). In conclusion, a longer varnish retention time than the usually recommended could improve the anticaries effect of Duraphat® varnish, allowing that NaF particles, initially insoluble in the varnish matrix, prolong the reactivity with enamel.
publisher Fundação Odontológica de Ribeirão Preto
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402014000200160
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