HIV-1 RNA detection in the amniotic fluid of HIV-infected pregnant women

HIV-1 RNA detection in the amniotic fluid of HIV-infected pregnant women

This study is aimed at evaluating the potential to detect human immunodeficiency virus (HIV) in amniotic fluid (AF) collected at delivery from 40 HIV-positive pregnant women. Thirty patients had a plasma viral load (VL) below 1,000 copies/mL at delivery. VL was positive in three AF samples. No significant association was found between the HIV-1 RNA in AF and the maternal plasma samples. There was no HIV vertical transmission detected.

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Bibliographic Details
Main Authors: Lobato,Ana Christina, Aguiar,Regina Amélia, Aleixo,Agdemir Waléria, Andrade,Beatriz Amélia, Cavallo,Ines Katherina, Kakehasi,Fabiana Maria, Pinto,Jorge Andrade, Melo,Victor Hugo
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000500021
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Summary:This study is aimed at evaluating the potential to detect human immunodeficiency virus (HIV) in amniotic fluid (AF) collected at delivery from 40 HIV-positive pregnant women. Thirty patients had a plasma viral load (VL) below 1,000 copies/mL at delivery. VL was positive in three AF samples. No significant association was found between the HIV-1 RNA in AF and the maternal plasma samples. There was no HIV vertical transmission detected.

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