Burkitt-like lymphoma in an infant: a case report

Childhood non-Hodgkin's lymphomas, including Burkitt and Burkitt-like, are rarely diagnosed in infants. A case of B-cell lymphoma in a 13-month-old girl with extensive abdominal disease, ascites, pleural effusion, and tumor lysis syndrome is reported. Phenotypic analysis showed a germinal center B-cell phenotype, and a B-cell clonality was confirmed by polymerase chain reaction. There was no evidence of Epstein-Barr and HIV infection. The case herein reported emphasizes the need for considering the diagnosis of lymphoma even in very young children.

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Bibliographic Details
Main Authors: Klumb,Claudete Esteves, Resende,Lídia Maria Magalhães de, Stefanoff,Claudio Gustavo, Vicuña,Carlos Humberto, Renault,Ilana Zalcberg, Maia,Raquel Ciuvalschi
Format: Digital revista
Language:English
Published: Faculdade de Medicina / Universidade de São Paulo - FM/USP 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0041-87812003000100007
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Summary:Childhood non-Hodgkin's lymphomas, including Burkitt and Burkitt-like, are rarely diagnosed in infants. A case of B-cell lymphoma in a 13-month-old girl with extensive abdominal disease, ascites, pleural effusion, and tumor lysis syndrome is reported. Phenotypic analysis showed a germinal center B-cell phenotype, and a B-cell clonality was confirmed by polymerase chain reaction. There was no evidence of Epstein-Barr and HIV infection. The case herein reported emphasizes the need for considering the diagnosis of lymphoma even in very young children.