No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration. Conclusion: At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.

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Bibliographic Details
Main Authors: Fragoso,Yara Dadalti, Adoni,Tarso, Alves-Leon,Soniza Vieira, Apostolos-Pereira,Samira L., Arruda,Walter Oleschko, Brooks,Joseph B. Bidin, Cal,Henrique S. Rodrigues, Damasceno,Carlos A. Albuquerque, Gama,Paulo Diniz, Goncalves,Marcus V. Magno, Jesus,Carlos A. da Silva de, Machado,Suzana C. Nunes, Mansur,Letícia Fezer, Matta,Andre P. da Cunha, Mendes,Maria Fernanda, Morales,Rogerio Rizo, Nobrega-Jr,Adaucto Wanderley da, Parolin,Monica K. Fiuza, Peres,Mario Pietro, Ribeiro,Marlise de Castro, Ruocco,Heloisa Helena, Scherpenhuijzen,Simone, Siquinelli,Fabio, Stoney,Patrick N., Varela,Daniel Lima, Eboni,Audred Cristina Biondo, Spessotto,Caroline Vieira, Rocha,Elisa Teixeira da, Lacerda,Pamela Emanuele
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000100003
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Summary:ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration. Conclusion: At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.

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