Multiple system atrophy: clinical-radiological correlation. Report of two cases

Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. We think that brain MRI might increase the accuracy diagnostic of MSA.

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Bibliographic Details
Main Authors: Albuquerque,Adolfo V. de, Freitas,Marcos R.G. de, Cincinatus,Daniel, Harouche,Maria Beatriz B.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300029
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Description
Summary:Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. We think that brain MRI might increase the accuracy diagnostic of MSA.