Propylthiouracil and peripheral neuropathy

Peripheral neuropathy is a rare manifestation in hyperthyroidism. We describe the neurological manifestations of a 38 year old female with Graves' disease who developed peripheral neuropathy in the course of her treatment with propylthiouracil. After the drug was tapered off, the neurological signs disappeared. Therefore, we call attention for a possible toxic effect on peripheral nervous system caused by this drug.

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Bibliographic Details
Main Authors: Boekel,Valentina Van, Godoy,José Maurício, Lamy,Luiz A., Assuf,Samira, Meyer Neto,João G. Corrêa, Balassiano,Salim L., Prata,Luiz E.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 1992
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1992000200021
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Description
Summary:Peripheral neuropathy is a rare manifestation in hyperthyroidism. We describe the neurological manifestations of a 38 year old female with Graves' disease who developed peripheral neuropathy in the course of her treatment with propylthiouracil. After the drug was tapered off, the neurological signs disappeared. Therefore, we call attention for a possible toxic effect on peripheral nervous system caused by this drug.