Periodic breathing and O2 saturation in relation to sleep stages at high altitude

This study was designed to compare sleep organization at high altitude (HA) and sea level (SL) and to estimate the extent periodic breathing (PB) negatively influences arterial O2, saturation (SaO2). Six lowlanders were studied at SL and after 3 weeks spent at 3,80O m (La Paz, Bolivia). Three EEG leads, EOG, submental EMG, chest and abdominal motion, temperature of ventilated gas, and SaO2 were polygraphically recorded. Comparison of HA ond SL data disclosed that: 1) Sleep organization was identical, with the same percentage of REM and stage 4. 2) PB (cycle length: 20 s; central apnea: 9 s) occurred in three subiects during all stages of sleep except REM (43-460% of total sleep). A periodic lowering in hearf rate occurred during ventilotory oscillation. 3) During PB, SaO2, oscillated very regularly from 78-90%, which resulted in a mean SaO2, value calculated during oscillations similar to that of the non-periodic breathers. We conclude that lung O2, uptake during PB is preserwed.

Bibliographic Details

Main Authors:	Normad, Hervé, Barragán, Mario, Benoit, Odile, Bailliart, Olivier, Raynaud, Jeanne
Format:	Article biblioteca
Language:	English
Published:	Aviat. Space Environ Med. 1990
Subjects:	RESPIRACIÓN PERIÓDICA, SATURACIÓN DE OXÍGENO, SUEÑO, GRAN ALTURA,
Online Access:	http://repositorio.umsa.bo/xmlui/handle/123456789/10995
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