Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh
Enteric pathogens can be transmitted through multiple environmental pathways, yet little is known about the relative contribution of each pathway to diarrhea risk among children. We aimed to identify fecal transmission pathways in the household environment associated with prospectively measured child diarrhea in rural Bangladesh. We measured the presence and levels of Escherichia coli in tube wells, stored drinking water, pond water, child hand rinses, courtyard soil, flies, and food in 1843 households. Gastrointestinal symptoms among children ages 0–60 months were recorded concurrently at the time of environmental sample collection and again a median of 6 days later. Incident diarrhea (3 or more loose stools in a 24-h period) was positively associated with the concentration of E. coli on child hands measured on the first visit (incidence rate ratio [IRR] = 1.23, 95% CI 1.06, 1.43 for a log10 increase), while other pathways were not associated. In cross-sectional analysis, there were no associations between concurrently measured environmental contamination and diarrhea. Our findings suggest higher levels of E. coli on child hands are strongly associated with subsequent diarrheal illness rates among children in rural Bangladesh.
Saved in:
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Journal Article biblioteca |
| Published: |
American Chemical Society
2018-06-14
|
| Subjects: | DIARRHEA, DRINKING WATER, WATER AND SANITATION, ENVIRONMENTAL CONTAMINATION, |
| Online Access: | http://hdl.handle.net/10986/31344 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dig-okr-1098631344 |
|---|---|
| record_format |
koha |
| spelling |
dig-okr-10986313442021-05-25T10:54:36Z Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh Pickering, Amy J. Ercumen, Ayse Arnold, Benjamin F. Kwong, Laura H. Parvez, Sarker Masud Alam, Mahfuja Sen, Debashis Islam, Sharmin Kullman, Craig Chase, Claire Ahmed, Rokeya Unicomb, Leanne Colford, John M., Jr. Luby, Stephen P. DIARRHEA DRINKING WATER WATER AND SANITATION ENVIRONMENTAL CONTAMINATION Enteric pathogens can be transmitted through multiple environmental pathways, yet little is known about the relative contribution of each pathway to diarrhea risk among children. We aimed to identify fecal transmission pathways in the household environment associated with prospectively measured child diarrhea in rural Bangladesh. We measured the presence and levels of Escherichia coli in tube wells, stored drinking water, pond water, child hand rinses, courtyard soil, flies, and food in 1843 households. Gastrointestinal symptoms among children ages 0–60 months were recorded concurrently at the time of environmental sample collection and again a median of 6 days later. Incident diarrhea (3 or more loose stools in a 24-h period) was positively associated with the concentration of E. coli on child hands measured on the first visit (incidence rate ratio [IRR] = 1.23, 95% CI 1.06, 1.43 for a log10 increase), while other pathways were not associated. In cross-sectional analysis, there were no associations between concurrently measured environmental contamination and diarrhea. Our findings suggest higher levels of E. coli on child hands are strongly associated with subsequent diarrheal illness rates among children in rural Bangladesh. 2019-03-05T20:50:17Z 2019-03-05T20:50:17Z 2018-06-14 Journal Article Environmental Science and Technology http://hdl.handle.net/10986/31344 CC BY 4.0 http://creativecommons.org/licenses/by/4.0 World Bank American Chemical Society Publications & Research :: Journal Article Publications & Research South Asia Bangladesh |
| institution |
Banco Mundial |
| collection |
DSpace |
| country |
Estados Unidos |
| countrycode |
US |
| component |
Bibliográfico |
| access |
En linea |
| databasecode |
dig-okr |
| tag |
biblioteca |
| region |
America del Norte |
| libraryname |
Biblioteca del Banco Mundial |
| topic |
DIARRHEA DRINKING WATER WATER AND SANITATION ENVIRONMENTAL CONTAMINATION DIARRHEA DRINKING WATER WATER AND SANITATION ENVIRONMENTAL CONTAMINATION |
| spellingShingle |
DIARRHEA DRINKING WATER WATER AND SANITATION ENVIRONMENTAL CONTAMINATION DIARRHEA DRINKING WATER WATER AND SANITATION ENVIRONMENTAL CONTAMINATION Pickering, Amy J. Ercumen, Ayse Arnold, Benjamin F. Kwong, Laura H. Parvez, Sarker Masud Alam, Mahfuja Sen, Debashis Islam, Sharmin Kullman, Craig Chase, Claire Ahmed, Rokeya Unicomb, Leanne Colford, John M., Jr. Luby, Stephen P. Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh |
| description |
Enteric pathogens can be transmitted through multiple environmental pathways, yet little is known about the relative contribution of each pathway to diarrhea risk among children. We aimed to identify fecal transmission pathways in the household environment associated with prospectively measured child diarrhea in rural Bangladesh. We measured the presence and levels of Escherichia coli in tube wells, stored drinking water, pond water, child hand rinses, courtyard soil, flies, and food in 1843 households. Gastrointestinal symptoms among children ages 0–60 months were recorded concurrently at the time of environmental sample collection and again a median of 6 days later. Incident diarrhea (3 or more loose stools in a 24-h period) was positively associated with the concentration of E. coli on child hands measured on the first visit (incidence rate ratio [IRR] = 1.23, 95% CI 1.06, 1.43 for a log10 increase), while other pathways were not associated. In cross-sectional analysis, there were no associations between concurrently measured environmental contamination and diarrhea. Our findings suggest higher levels of E. coli on child hands are strongly associated with subsequent diarrheal illness rates among children in rural Bangladesh. |
| format |
Journal Article |
| topic_facet |
DIARRHEA DRINKING WATER WATER AND SANITATION ENVIRONMENTAL CONTAMINATION |
| author |
Pickering, Amy J. Ercumen, Ayse Arnold, Benjamin F. Kwong, Laura H. Parvez, Sarker Masud Alam, Mahfuja Sen, Debashis Islam, Sharmin Kullman, Craig Chase, Claire Ahmed, Rokeya Unicomb, Leanne Colford, John M., Jr. Luby, Stephen P. |
| author_facet |
Pickering, Amy J. Ercumen, Ayse Arnold, Benjamin F. Kwong, Laura H. Parvez, Sarker Masud Alam, Mahfuja Sen, Debashis Islam, Sharmin Kullman, Craig Chase, Claire Ahmed, Rokeya Unicomb, Leanne Colford, John M., Jr. Luby, Stephen P. |
| author_sort |
Pickering, Amy J. |
| title |
Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh |
| title_short |
Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh |
| title_full |
Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh |
| title_fullStr |
Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh |
| title_full_unstemmed |
Fecal Indicator Bacteria along Multiple Environmental Transmission Pathways (Water, Hands, Food, Soil, Flies) and Subsequent Child Diarrhea in Rural Bangladesh |
| title_sort |
fecal indicator bacteria along multiple environmental transmission pathways (water, hands, food, soil, flies) and subsequent child diarrhea in rural bangladesh |
| publisher |
American Chemical Society |
| publishDate |
2018-06-14 |
| url |
http://hdl.handle.net/10986/31344 |
| work_keys_str_mv |
AT pickeringamyj fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT ercumenayse fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT arnoldbenjaminf fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT kwonglaurah fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT parvezsarkermasud fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT alammahfuja fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT sendebashis fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT islamsharmin fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT kullmancraig fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT chaseclaire fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT ahmedrokeya fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT unicombleanne fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT colfordjohnmjr fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh AT lubystephenp fecalindicatorbacteriaalongmultipleenvironmentaltransmissionpathwayswaterhandsfoodsoilfliesandsubsequentchilddiarrheainruralbangladesh |
| _version_ |
1756575311939502080 |