A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic.
In this paper we present an extension of an automata approach proposed by S. Blower (1998) to describe the tuberculosis progression in a bi-dimensional space. In our extended model, the vaccination was included as an inhibitory variable in order to study its influence on the behavior of the tuberculosis spread. Our simulations showed that the earlier the vaccine is administered in the population, the lower the number of infected individuals, as expected for an in vivo system. However, our results also indicated that although the usual vaccination processes help reducing the strength of infection, the disease is not extinct, remaining the endemic state at low levels. These results strongly suggest that further actions are needed to increase the effectiveness of immunizations.
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Format: | Artigo de periódico biblioteca |
Language: | English eng |
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2014-07-11
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Subjects: | Cellular automata., Tuberculose, Simulação., Tuberculosis, Computer simulation, |
Online Access: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/990390 |
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dig-alice-doc-9903902017-08-16T00:44:31Z A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. FRONZA, C. F. ANSELMO, J. MARQUES, J. L. B. PINTARELLI, G. B. CASTRO, A. de CARLOS FREDERICO FRONZA, UFSC; JANIO ANSELMO, UFSC; JEFFERSON LUIZ BRUM MARQUES, UFSC; GUILHERME BRASIL PINTARELLI, UFSC; ALEXANDRE DE CASTRO, CNPTIA. Cellular automata. Tuberculose Simulação. Tuberculosis Computer simulation In this paper we present an extension of an automata approach proposed by S. Blower (1998) to describe the tuberculosis progression in a bi-dimensional space. In our extended model, the vaccination was included as an inhibitory variable in order to study its influence on the behavior of the tuberculosis spread. Our simulations showed that the earlier the vaccine is administered in the population, the lower the number of infected individuals, as expected for an in vivo system. However, our results also indicated that although the usual vaccination processes help reducing the strength of infection, the disease is not extinct, remaining the endemic state at low levels. These results strongly suggest that further actions are needed to increase the effectiveness of immunizations. 2014-07-11T11:11:11Z 2014-07-11T11:11:11Z 2014-07-11 2014 2014-07-23T11:11:11Z Artigo de periódico International Journal of Engineering Research and Applications, Delhi, v. 4, n. 6, p. 233-238, June 2014. http://www.alice.cnptia.embrapa.br/alice/handle/doc/990390 en eng openAccess |
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Cellular automata. Tuberculose Simulação. Tuberculosis Computer simulation Cellular automata. Tuberculose Simulação. Tuberculosis Computer simulation |
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Cellular automata. Tuberculose Simulação. Tuberculosis Computer simulation Cellular automata. Tuberculose Simulação. Tuberculosis Computer simulation FRONZA, C. F. ANSELMO, J. MARQUES, J. L. B. PINTARELLI, G. B. CASTRO, A. de A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. |
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In this paper we present an extension of an automata approach proposed by S. Blower (1998) to describe the tuberculosis progression in a bi-dimensional space. In our extended model, the vaccination was included as an inhibitory variable in order to study its influence on the behavior of the tuberculosis spread. Our simulations showed that the earlier the vaccine is administered in the population, the lower the number of infected individuals, as expected for an in vivo system. However, our results also indicated that although the usual vaccination processes help reducing the strength of infection, the disease is not extinct, remaining the endemic state at low levels. These results strongly suggest that further actions are needed to increase the effectiveness of immunizations. |
author2 |
CARLOS FREDERICO FRONZA, UFSC; JANIO ANSELMO, UFSC; JEFFERSON LUIZ BRUM MARQUES, UFSC; GUILHERME BRASIL PINTARELLI, UFSC; ALEXANDRE DE CASTRO, CNPTIA. |
author_facet |
CARLOS FREDERICO FRONZA, UFSC; JANIO ANSELMO, UFSC; JEFFERSON LUIZ BRUM MARQUES, UFSC; GUILHERME BRASIL PINTARELLI, UFSC; ALEXANDRE DE CASTRO, CNPTIA. FRONZA, C. F. ANSELMO, J. MARQUES, J. L. B. PINTARELLI, G. B. CASTRO, A. de |
format |
Artigo de periódico |
topic_facet |
Cellular automata. Tuberculose Simulação. Tuberculosis Computer simulation |
author |
FRONZA, C. F. ANSELMO, J. MARQUES, J. L. B. PINTARELLI, G. B. CASTRO, A. de |
author_sort |
FRONZA, C. F. |
title |
A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. |
title_short |
A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. |
title_full |
A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. |
title_fullStr |
A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. |
title_full_unstemmed |
A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. |
title_sort |
blower-like approach to predict the effectiveness of vaccines in a tb dynamic. |
publishDate |
2014-07-11 |
url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/990390 |
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