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Antibiotics [electronic resource] : Containing the Beta-Lactam Structure, Part II /
12 Bacterial Enzymes Interacting with ?-Lactam Antibiotics -- A. Introduction -- B. Bacterial Proteins Binding ?-Lactam Antibiotics -- C. Enzymes Inhibited by ?-Lactam Antibiotics -- D. ?-Lactamases -- E. Interaction with the ?-Lactam Nucleus -- F. Concluding Remarks -- References -- 13 In Vitro and In Vivo Laboratory Evaluation of ?-Lactam Antibiotics -- A. Historical -- B. ?-Lactam Laboratory Evaluation Procedures -- C. Representative ?-Lactam Agents -- References -- 14 ?-Lactam Antibiotics: Structure-Activity Relationships -- A. Introduction: Scope -- B. Clinically Useful Penicillins -- C. Clinically Useful Cephalosporins -- D. Nonclassic ?-Lactams -- E. Other Structure-Activity Relationships -- References -- 15 Pharmacokinetics of ?-Lactam Antibiotics -- A. Introduction -- B. Penicillins -- C. Cephalosporins -- D. Other ?-Lactam Antibiotics -- References -- 16 Toxicology of ?-Lactam Antibiotics -- A. Introduction -- B. Local Reactions to Parenteral Administration -- C. Gastrointestinal Side Effects -- D. Immunologically Mediated Toxicity -- E Immune Hemolytic Anemia -- F. Neutropenia -- G. Disorders of Hemostasis -- H. Interstitial Nephritis and Cystitis -- I. Nephrotoxicity -- J. Hepatic Toxicity -- K. Neurotoxicity -- L. Disulfiram-Like Reactions -- M. Newer ?-Lactams -- References -- 17 Therapeutic Application of ?-Lactam Antibiotics -- A. Introduction -- B. Penicillins in the Therapy of Human Infections -- C. Cephalosporins in the Therapy of Human Infections -- D. Antibacterial Chemoprophylaxis with the ?-Lactam Antiobiotics -- E. Use of ?-Lactam Antibiotics in Dental Medicine -- F. Use of ?-Lactam Antibiotics in Veterinary Practice -- References.
| Main Authors: | , , |
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| Format: | Texto biblioteca |
| Language: | eng |
| Published: |
Berlin, Heidelberg : Springer Berlin Heidelberg,
1983
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| Subjects: | Medicine., Pharmacy., Pharmacology., Biomedicine., Pharmacology/Toxicology., |
| Online Access: | http://dx.doi.org/10.1007/978-3-642-68901-7 |
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| Summary: | 12 Bacterial Enzymes Interacting with ?-Lactam Antibiotics -- A. Introduction -- B. Bacterial Proteins Binding ?-Lactam Antibiotics -- C. Enzymes Inhibited by ?-Lactam Antibiotics -- D. ?-Lactamases -- E. Interaction with the ?-Lactam Nucleus -- F. Concluding Remarks -- References -- 13 In Vitro and In Vivo Laboratory Evaluation of ?-Lactam Antibiotics -- A. Historical -- B. ?-Lactam Laboratory Evaluation Procedures -- C. Representative ?-Lactam Agents -- References -- 14 ?-Lactam Antibiotics: Structure-Activity Relationships -- A. Introduction: Scope -- B. Clinically Useful Penicillins -- C. Clinically Useful Cephalosporins -- D. Nonclassic ?-Lactams -- E. Other Structure-Activity Relationships -- References -- 15 Pharmacokinetics of ?-Lactam Antibiotics -- A. Introduction -- B. Penicillins -- C. Cephalosporins -- D. Other ?-Lactam Antibiotics -- References -- 16 Toxicology of ?-Lactam Antibiotics -- A. Introduction -- B. Local Reactions to Parenteral Administration -- C. Gastrointestinal Side Effects -- D. Immunologically Mediated Toxicity -- E Immune Hemolytic Anemia -- F. Neutropenia -- G. Disorders of Hemostasis -- H. Interstitial Nephritis and Cystitis -- I. Nephrotoxicity -- J. Hepatic Toxicity -- K. Neurotoxicity -- L. Disulfiram-Like Reactions -- M. Newer ?-Lactams -- References -- 17 Therapeutic Application of ?-Lactam Antibiotics -- A. Introduction -- B. Penicillins in the Therapy of Human Infections -- C. Cephalosporins in the Therapy of Human Infections -- D. Antibacterial Chemoprophylaxis with the ?-Lactam Antiobiotics -- E. Use of ?-Lactam Antibiotics in Dental Medicine -- F. Use of ?-Lactam Antibiotics in Veterinary Practice -- References. |
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