Perianal Paget's disease

Perianal Paget's disease

ABSTRACT Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers. Due to the lack of distinctive features and nonspecific presenting symptoms, Paget's disease may be misdiagnosed as other conditions, thus delaying the correct diagnosis. We report a case of extramammary Paget's disease in the perianal region that initially presented as an irregular, circumferential, scaling lesion with eczematous eruptions. Immunology and immunohistochemistry confirmed the diagnosis. Although surgery is the standard treatment, the patient opted for pelvic radiotherapy associated with radiosensitizing chemotherapy.

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Main Authors: Cassol,Ornella Sari, Pastorello,Júlia, Oliveira,Bruna de, Lenhardt,Lucas Henrique, Montagna,Suéllen, Pietrobelli,Vanessa Locatelli
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Coloproctologia 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000300262
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spelling oai:scielo:S2237-936320190003002622019-09-26Perianal Paget's diseaseCassol,Ornella SariPastorello,JúliaOliveira,Bruna deLenhardt,Lucas HenriqueMontagna,SuéllenPietrobelli,Vanessa Locatelli Paget's disease Extramammary Paget's disease Perianal ABSTRACT Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers. Due to the lack of distinctive features and nonspecific presenting symptoms, Paget's disease may be misdiagnosed as other conditions, thus delaying the correct diagnosis. We report a case of extramammary Paget's disease in the perianal region that initially presented as an irregular, circumferential, scaling lesion with eczematous eruptions. Immunology and immunohistochemistry confirmed the diagnosis. Although surgery is the standard treatment, the patient opted for pelvic radiotherapy associated with radiosensitizing chemotherapy.info:eu-repo/semantics/openAccessSociedade Brasileira de ColoproctologiaJournal of Coloproctology (Rio de Janeiro) v.39 n.3 20192019-09-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000300262en10.1016/j.jcol.2019.05.011
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Cassol,Ornella Sari
Pastorello,Júlia
Oliveira,Bruna de
Lenhardt,Lucas Henrique
Montagna,Suéllen
Pietrobelli,Vanessa Locatelli
spellingShingle Cassol,Ornella Sari
Pastorello,Júlia
Oliveira,Bruna de
Lenhardt,Lucas Henrique
Montagna,Suéllen
Pietrobelli,Vanessa Locatelli
Perianal Paget's disease
author_facet Cassol,Ornella Sari
Pastorello,Júlia
Oliveira,Bruna de
Lenhardt,Lucas Henrique
Montagna,Suéllen
Pietrobelli,Vanessa Locatelli
author_sort Cassol,Ornella Sari
title Perianal Paget's disease
title_short Perianal Paget's disease
title_full Perianal Paget's disease
title_fullStr Perianal Paget's disease
title_full_unstemmed Perianal Paget's disease
title_sort perianal paget's disease
description ABSTRACT Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers. Due to the lack of distinctive features and nonspecific presenting symptoms, Paget's disease may be misdiagnosed as other conditions, thus delaying the correct diagnosis. We report a case of extramammary Paget's disease in the perianal region that initially presented as an irregular, circumferential, scaling lesion with eczematous eruptions. Immunology and immunohistochemistry confirmed the diagnosis. Although surgery is the standard treatment, the patient opted for pelvic radiotherapy associated with radiosensitizing chemotherapy.
publisher Sociedade Brasileira de Coloproctologia
publishDate 2019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632019000300262
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AT oliveirabrunade perianalpagetsdisease
AT lenhardtlucashenrique perianalpagetsdisease
AT montagnasuellen perianalpagetsdisease
AT pietrobellivanessalocatelli perianalpagetsdisease
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