Fulminating herpes simplex hepatitis

Fulminating herpes simplex hepatitis

ABSTRACT Herpes simplex virus (HSV) is a rare cause of acute hepatitis in patients with chronic immunosuppression, including Crohn’s disease. HSV hepatitis has the propensity to cause acute liver failure and death. The presenting signs and symptoms can be nonspecific, thereby causing the diagnosis to go overlooked with inadequate management, leading to a high mortality rate. We report a case of a 31-year-old male on chronic prednisone treatment for Crohn’s disease who unexpectedly died. Subsequently, an autopsy showed HSV hepatitis as the cause of death. Thus, although a rare complication, HSV hepatitis should always be kept in mind as a fatal complication in patients with acute hepatitis and chronic immunosuppression.

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Bibliographic Details
Main Authors: Ahmed,Raheel, Green,Kesley, Litovsky,Silvio, Diffalha,Sameer Al
Format: Digital revista
Language:English
Published: Hospital Universitário da Universidade de São Paulo 2022
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602022000100409
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spelling oai:scielo:S2236-196020220001004092022-12-13Fulminating herpes simplex hepatitisAhmed,RaheelGreen,KesleyLitovsky,SilvioDiffalha,Sameer Al Herpes Simplex Virus Hepatitis Crohn’s Disease Prednisone ABSTRACT Herpes simplex virus (HSV) is a rare cause of acute hepatitis in patients with chronic immunosuppression, including Crohn’s disease. HSV hepatitis has the propensity to cause acute liver failure and death. The presenting signs and symptoms can be nonspecific, thereby causing the diagnosis to go overlooked with inadequate management, leading to a high mortality rate. We report a case of a 31-year-old male on chronic prednisone treatment for Crohn’s disease who unexpectedly died. Subsequently, an autopsy showed HSV hepatitis as the cause of death. Thus, although a rare complication, HSV hepatitis should always be kept in mind as a fatal complication in patients with acute hepatitis and chronic immunosuppression.info:eu-repo/semantics/openAccessHospital Universitário da Universidade de São PauloAutopsy and Case Reports v.12 20222022-01-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602022000100409en10.4322/acr.2021.410
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Ahmed,Raheel
Green,Kesley
Litovsky,Silvio
Diffalha,Sameer Al
spellingShingle Ahmed,Raheel
Green,Kesley
Litovsky,Silvio
Diffalha,Sameer Al
Fulminating herpes simplex hepatitis
author_facet Ahmed,Raheel
Green,Kesley
Litovsky,Silvio
Diffalha,Sameer Al
author_sort Ahmed,Raheel
title Fulminating herpes simplex hepatitis
title_short Fulminating herpes simplex hepatitis
title_full Fulminating herpes simplex hepatitis
title_fullStr Fulminating herpes simplex hepatitis
title_full_unstemmed Fulminating herpes simplex hepatitis
title_sort fulminating herpes simplex hepatitis
description ABSTRACT Herpes simplex virus (HSV) is a rare cause of acute hepatitis in patients with chronic immunosuppression, including Crohn’s disease. HSV hepatitis has the propensity to cause acute liver failure and death. The presenting signs and symptoms can be nonspecific, thereby causing the diagnosis to go overlooked with inadequate management, leading to a high mortality rate. We report a case of a 31-year-old male on chronic prednisone treatment for Crohn’s disease who unexpectedly died. Subsequently, an autopsy showed HSV hepatitis as the cause of death. Thus, although a rare complication, HSV hepatitis should always be kept in mind as a fatal complication in patients with acute hepatitis and chronic immunosuppression.
publisher Hospital Universitário da Universidade de São Paulo
publishDate 2022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602022000100409
work_keys_str_mv AT ahmedraheel fulminatingherpessimplexhepatitis
AT greenkesley fulminatingherpessimplexhepatitis
AT litovskysilvio fulminatingherpessimplexhepatitis
AT diffalhasameeral fulminatingherpessimplexhepatitis
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