Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens
ABSTRACT The chronological skin aging is a progressive and natural process with genetic and physiological changes. However, ultraviolet (UV) radiation may accelerate the oxidative stress, generating carcinogenesis and photoaging. Natural compounds and their applications are considered a trend in the cosmetic market. The protein-based film-forming compounds play an important role, once it collaborates for the better distribution of sunscreens on the skin. Here we investigated the in vitro photoprotective effectiveness of sunscreens containing the hydrolyzed collagen associated with UVA, UVB and/or inorganic filters. Sunscreens were developed with octocrylene (7.5%), butyl methoxydibenzoylmethane (avobenzone) (3.0%) and/or titanium dioxide (5.0%), associated or not with the hydrolyzed collagen (3.0%). In vitro photoprotective effectiveness was determined in a Labsphere(r) UV2000S by the establishment of the sun protection factor (SPF) and critical wavelength (nm) values. Physicochemical and organoleptic characteristics were also assayed. The hydrolyzed collagen subjectively improved the formulation sensory characteristics. However, this bioactive compound led to a decrease of the SPF values of the photoprotective formulations containing octocrylene alone and octocrylene + butyl methoxydibenzoylmethane + TiO2. This inadequate interaction may be considered during the development of new sunscreens intended to contain protein-based components.
Main Authors: | , , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
2017
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200611 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S1984-82502017000200611 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S1984-825020170002006112017-06-20Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreensPeres,Daniela D'AlmeidaHubner,AlexandraOliveira,Camila Areias deAlmeida,Tania Santos deKaneko,Telma MaryConsiglieri,Vladi OlgaPinto,Claudinéia Aparecida Sales de OliveiraVelasco,Maria Valéria RoblesBaby,André Rolim Hydrolyzed collagen/protective effects Photoprotector/effectiveness Photoprotector/in vitro study Sun protection factor Sunscreen/UV filter Critical wavelength ABSTRACT The chronological skin aging is a progressive and natural process with genetic and physiological changes. However, ultraviolet (UV) radiation may accelerate the oxidative stress, generating carcinogenesis and photoaging. Natural compounds and their applications are considered a trend in the cosmetic market. The protein-based film-forming compounds play an important role, once it collaborates for the better distribution of sunscreens on the skin. Here we investigated the in vitro photoprotective effectiveness of sunscreens containing the hydrolyzed collagen associated with UVA, UVB and/or inorganic filters. Sunscreens were developed with octocrylene (7.5%), butyl methoxydibenzoylmethane (avobenzone) (3.0%) and/or titanium dioxide (5.0%), associated or not with the hydrolyzed collagen (3.0%). In vitro photoprotective effectiveness was determined in a Labsphere(r) UV2000S by the establishment of the sun protection factor (SPF) and critical wavelength (nm) values. Physicochemical and organoleptic characteristics were also assayed. The hydrolyzed collagen subjectively improved the formulation sensory characteristics. However, this bioactive compound led to a decrease of the SPF values of the photoprotective formulations containing octocrylene alone and octocrylene + butyl methoxydibenzoylmethane + TiO2. This inadequate interaction may be considered during the development of new sunscreens intended to contain protein-based components.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Faculdade de Ciências FarmacêuticasBrazilian Journal of Pharmaceutical Sciences v.53 n.2 20172017-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200611en10.1590/s2175-97902017000216119 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Peres,Daniela D'Almeida Hubner,Alexandra Oliveira,Camila Areias de Almeida,Tania Santos de Kaneko,Telma Mary Consiglieri,Vladi Olga Pinto,Claudinéia Aparecida Sales de Oliveira Velasco,Maria Valéria Robles Baby,André Rolim |
spellingShingle |
Peres,Daniela D'Almeida Hubner,Alexandra Oliveira,Camila Areias de Almeida,Tania Santos de Kaneko,Telma Mary Consiglieri,Vladi Olga Pinto,Claudinéia Aparecida Sales de Oliveira Velasco,Maria Valéria Robles Baby,André Rolim Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
author_facet |
Peres,Daniela D'Almeida Hubner,Alexandra Oliveira,Camila Areias de Almeida,Tania Santos de Kaneko,Telma Mary Consiglieri,Vladi Olga Pinto,Claudinéia Aparecida Sales de Oliveira Velasco,Maria Valéria Robles Baby,André Rolim |
author_sort |
Peres,Daniela D'Almeida |
title |
Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
title_short |
Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
title_full |
Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
title_fullStr |
Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
title_full_unstemmed |
Hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
title_sort |
hydrolyzed collagen interferes with in vitro photoprotective effectiveness of sunscreens |
description |
ABSTRACT The chronological skin aging is a progressive and natural process with genetic and physiological changes. However, ultraviolet (UV) radiation may accelerate the oxidative stress, generating carcinogenesis and photoaging. Natural compounds and their applications are considered a trend in the cosmetic market. The protein-based film-forming compounds play an important role, once it collaborates for the better distribution of sunscreens on the skin. Here we investigated the in vitro photoprotective effectiveness of sunscreens containing the hydrolyzed collagen associated with UVA, UVB and/or inorganic filters. Sunscreens were developed with octocrylene (7.5%), butyl methoxydibenzoylmethane (avobenzone) (3.0%) and/or titanium dioxide (5.0%), associated or not with the hydrolyzed collagen (3.0%). In vitro photoprotective effectiveness was determined in a Labsphere(r) UV2000S by the establishment of the sun protection factor (SPF) and critical wavelength (nm) values. Physicochemical and organoleptic characteristics were also assayed. The hydrolyzed collagen subjectively improved the formulation sensory characteristics. However, this bioactive compound led to a decrease of the SPF values of the photoprotective formulations containing octocrylene alone and octocrylene + butyl methoxydibenzoylmethane + TiO2. This inadequate interaction may be considered during the development of new sunscreens intended to contain protein-based components. |
publisher |
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas |
publishDate |
2017 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200611 |
work_keys_str_mv |
AT peresdanieladalmeida hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT hubneralexandra hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT oliveiracamilaareiasde hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT almeidataniasantosde hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT kanekotelmamary hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT consiglierivladiolga hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT pintoclaudineiaaparecidasalesdeoliveira hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT velascomariavaleriarobles hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens AT babyandrerolim hydrolyzedcollageninterfereswithinvitrophotoprotectiveeffectivenessofsunscreens |
_version_ |
1756437815218929664 |