Photochemical Transformations of Chalcone-Vitamin E Hybrids

Abstract Chalcone-vitamin E hybrids 6’-O-tosyl-3,4,5-trimethoxy-δ-tocopherol-chalcone (1), 3,4,5-trimethoxy-δ-tocopherol-chalcone (2), 6’-O-tosyl-3,4,5-trimethoxy-δ-tocopherol-retrochalcone (3) and 3,4,5-trimethoxy-δ-tocopherol-retrochalcone (4) were synthesized as part of a search for new biological activities in these types of derivatives. We report herein on the photoisomerization products of hybrids 1-4, and the effects of the solvent and substitution patterns in producing secondary products such as flavanone 6, 3-deoxyanthocyanidin 8, and hemiketal 10. Photochemically-induced changes are considered important since structural modifications and/or the presence of additional products can affect the biological activity of this type of semisynthetic hybrids.

Bibliographic Details

Main Authors:	Ceballos-Cruz,Jimmy Josué, Hélesbeux,Jean-Jacques, Viault,Guillaume, Séraphin,Denis, Mirón-Lopez,Gumersindo, Carballo,Rubén M., Richomme,Pascal, Peña-Rodríguez,Luis Manuel
Format:	Digital revista
Language:	English
Published:	Sociedad Química de México A.C. 2022
Online Access:	http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1870-249X2022000100120
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