New tendencies in non-surgical periodontal therapy

Abstract The aim of this review was to update the evidence of new approaches to non-surgical therapy (NSPT) in the treatment of periodontitis. Preclinical and clinical studies addressing the benefits of adjunctive antimicrobial photodynamic therapy, probiotics, prebiotics/synbiotics, statins, pro-resolving mediators, omega-6 and -3, ozone, and epigenetic therapy were scrutinized and discussed. Currently, the outcomes of these nine new approaches, when compared with subgingival debridement alone, did not demonstrate a significant added clinical benefit. However, some of these new alternative interventions may have the potential to improve the outcomes of NSPT alone. Future evidence based on randomized controlled clinical trials would help clinicians and patients in the selection of different adjunctive therapies.

Bibliographic Details

Main Authors:	HAAS,Alex Nogueira, FURLANETO,Flavia, GAIO,Eduardo José, GOMES,Sabrina Carvalho, PALIOTO,Daniela Bazan, CASTILHO,Rogerio Moraes, SANZ,Mariano, MESSORA,Michel Reis
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Pesquisa Odontológica - SBPqO 2021
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000300600
Tags:	Add Tag No Tags, Be the first to tag this record!