In vitro antibacterial activity of a silicone-based endodontic sealer and two conventional sealers

Abstract The aim of this study was to evaluate whether the modification in the silver component is capable of providing GuttaFlow 2 with antibacterial activity against Enterococcus faecalis compared with epoxy resin-based (AH Plus) and zinc oxide and eugenol-based (Endofill) sealers. The antibacterial activity was evaluated using a reference strain of E. faecalis (ATCC 29212). Freshly mixed sealers were subjected to the agar diffusion test (ADT), while the direct contact test (DCT) was performed after materials setting. ADT results were obtained through measurements, in millimeters, of the inhibition zones promoted by the materials, using a digital caliper. In DCT, values of CFU/mL promoted by the three sealers were compared in three experimental periods (1 min, 1 h, and 24 h). The data were analyzed using Kruskal-Wallis and Dunn post-hoc tests (p < 0.05). In both ADT and DCT, GuttaFlow 2 presented no effect against E. faecalis, while Endofill and AH Plus showed similar inhibition zones. Endofill was the only material capable of reducing bacterial growth in DCT. In conclusion, modifications in the silver particle of GuttaFlow 2 did not result in a sealer with antibacterial effect against E. faecalis.

Bibliographic Details

Main Authors:	WAINSTEIN,Marcela, MORGENTAL,Renata Dornelles, WALTRICK,Silvana Beltrami Gonçalves, OLIVEIRA,Sílvia Dias, VIER-PELISSER,Fabiana Vieira, FIGUEIREDO,José Antonio Poli, STEIER,Liviu, TAVARES,Cauana Oliva, SCARPARO,Roberta Kochenborger
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Pesquisa Odontológica - SBPqO 2016
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242016000100216
Tags:	Add Tag No Tags, Be the first to tag this record!