Unusual combination of gestational trophoblastic neoplasias: case report

Unusual combination of gestational trophoblastic neoplasias: case report

Gestational trophoblastic disease comprises a heterogeneous group of lesions arising from abnormal proliferation of trophoblastic cells. An elevation of human chorionic gonadotropin after evacuation of a molar pregnancy should suggest the hypothesis of a persistent gestational trophoblastic neoplasia. We present a rare case of coexistence of choriocarcinoma and placental-site trophoblastic tumor in the same tumor, whose diagnosis was made based on the correlation of morphological, microscopic and immunocytochemical studies, due to the difficulty in diagnosing these mixed tumors based on conventional histology only.

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Main Authors: Ramilo,Irina Dulce Tapadinhas Matos, Mendinhos,Gustavo Martins, Igreja,Fernando Antônio Ferreira da, Aleluia,Maria Clara Morais, Nogueira,Rosete Maria Amorim Novais, Gomes,Fernando Manuel Ribeiro, Pereira,José Manuel Silva
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442014000500375
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spelling oai:scielo:S1676-244420140005003752014-12-09Unusual combination of gestational trophoblastic neoplasias: case reportRamilo,Irina Dulce Tapadinhas MatosMendinhos,Gustavo MartinsIgreja,Fernando Antônio Ferreira daAleluia,Maria Clara MoraisNogueira,Rosete Maria Amorim NovaisGomes,Fernando Manuel RibeiroPereira,José Manuel Silva choriocarcinoma gestational trophoblast neoplasm chemotherapy Gestational trophoblastic disease comprises a heterogeneous group of lesions arising from abnormal proliferation of trophoblastic cells. An elevation of human chorionic gonadotropin after evacuation of a molar pregnancy should suggest the hypothesis of a persistent gestational trophoblastic neoplasia. We present a rare case of coexistence of choriocarcinoma and placental-site trophoblastic tumor in the same tumor, whose diagnosis was made based on the correlation of morphological, microscopic and immunocytochemical studies, due to the difficulty in diagnosing these mixed tumors based on conventional histology only.info:eu-repo/semantics/openAccessSociedade Brasileira de Patologia Clínica Jornal Brasileiro de Patologia e Medicina Laboratorial v.50 n.5 20142014-10-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442014000500375en10.5935/1676-2444.20140044
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Ramilo,Irina Dulce Tapadinhas Matos
Mendinhos,Gustavo Martins
Igreja,Fernando Antônio Ferreira da
Aleluia,Maria Clara Morais
Nogueira,Rosete Maria Amorim Novais
Gomes,Fernando Manuel Ribeiro
Pereira,José Manuel Silva
spellingShingle Ramilo,Irina Dulce Tapadinhas Matos
Mendinhos,Gustavo Martins
Igreja,Fernando Antônio Ferreira da
Aleluia,Maria Clara Morais
Nogueira,Rosete Maria Amorim Novais
Gomes,Fernando Manuel Ribeiro
Pereira,José Manuel Silva
Unusual combination of gestational trophoblastic neoplasias: case report
author_facet Ramilo,Irina Dulce Tapadinhas Matos
Mendinhos,Gustavo Martins
Igreja,Fernando Antônio Ferreira da
Aleluia,Maria Clara Morais
Nogueira,Rosete Maria Amorim Novais
Gomes,Fernando Manuel Ribeiro
Pereira,José Manuel Silva
author_sort Ramilo,Irina Dulce Tapadinhas Matos
title Unusual combination of gestational trophoblastic neoplasias: case report
title_short Unusual combination of gestational trophoblastic neoplasias: case report
title_full Unusual combination of gestational trophoblastic neoplasias: case report
title_fullStr Unusual combination of gestational trophoblastic neoplasias: case report
title_full_unstemmed Unusual combination of gestational trophoblastic neoplasias: case report
title_sort unusual combination of gestational trophoblastic neoplasias: case report
description Gestational trophoblastic disease comprises a heterogeneous group of lesions arising from abnormal proliferation of trophoblastic cells. An elevation of human chorionic gonadotropin after evacuation of a molar pregnancy should suggest the hypothesis of a persistent gestational trophoblastic neoplasia. We present a rare case of coexistence of choriocarcinoma and placental-site trophoblastic tumor in the same tumor, whose diagnosis was made based on the correlation of morphological, microscopic and immunocytochemical studies, due to the difficulty in diagnosing these mixed tumors based on conventional histology only.
publisher Sociedade Brasileira de Patologia Clínica
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442014000500375
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AT aleluiamariaclaramorais unusualcombinationofgestationaltrophoblasticneoplasiascasereport
AT nogueirarosetemariaamorimnovais unusualcombinationofgestationaltrophoblasticneoplasiascasereport
AT gomesfernandomanuelribeiro unusualcombinationofgestationaltrophoblasticneoplasiascasereport
AT pereirajosemanuelsilva unusualcombinationofgestationaltrophoblasticneoplasiascasereport
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