SYNTHESIS OF SOME SECONDARY AMINE DERIVATIVES BEARING A HETEROARYL FRAGMENT
Diverse N-(heteroarylmethyl)anilines were easily prepared from corresponding aldimines derived from commercially available aromatic aldehydes and anilines. New series of substituted NH-tetrahydroquinolines were also prepared using imino-Diels-Alder reaction between aldimines and N-vinylpyrrolidin-2-one in the presence of BF3.OEt2 and the multi-component condensation reactions using a friendly ecological catalyst (BiCl3). The secondary amines obtained bearing a heteroaryl moiety were tested as possible antibacterial and antifungal agents
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedad Chilena de Química
2004
|
| Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072004000400010 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|