Intra-articular injection with triamcinolone hexacetonide in patients with rheumatoid arthritis: prospective assessment of goniometry and joint inflammation parameters
Abstract Objectives: To evaluate local joint variables after intra-articular injection with triamcinolone hexacetonide in rheumatoid arthritis patients. Methods: We blindly and prospectively (baseline, 1, 4, 12 and 24 weeks) evaluated metacarpophalangeal, wrist, elbow, shoulder, knee and ankle joints after triamcinolone hexacetonide intra-articular injection by the following outcome measures: visual analogue scale 0–10 cm (VAS) for rest pain (VASR); VAS for movement pain (VASM); VAS for joint swelling (VASSw); flexion (FlexG) and extension (ExtG). Results: 289 patients (635 joints) were studied. VASSw (p < 0.001) and VASR (0.001 < p < 0.016) improved from T0 to T4, T12 and T24 for all joints. VASM improved from T0 to T4 (p < 0.021) for all joints; T0 to T12 (p < 0.023) for MCF and knee; T0 to T24 (p < 0.019) only for MCF and knee. FlexG improved from T0 to T4 (p < 0.001) for all joints; T0 to T12 (p < 0.001) and T0 to T24 (p < 0.02) only for MCF and knee. ExtG improved from T0 to T4 (p < 0.001) for all joints except for elbow; T0 to T12 (p = 0.003) for wrist, metacarpophalangeal and knee; and T0 to T24 (p = 0.014) for MCF and knee. Conclusion: VASSw responded better at short and medium term after IAI with triamcinolone hexacetonide in our sample of RA patients.
Main Authors: | Furtado,Rita Nely Vilar, Machado,Flávia Soares, Luz,Karine Rodrigues da, Santos,Marla Francisca dos, Konai,Monique Sayuri, Lopes,Roberta Vilela, Natour,Jamil |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Reumatologia
2017
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042017000200115 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Intra-articular triamcinolone hexacetonide injections in hands osteoarthritis – A double-blinded randomized controlled trial with a one year follow-up
by: Paschoal,Natalia de Oliva Spolidoro, et al.
Published: (2022) -
Inflammatory arthritis or osteoarthritis of the knee - Efficacy of intra-joint infiltration of methylprednisolone acetate versus triamcinolone acetonide or triamcinolone hexacetonide
by: Silvinato,Antonio, et al.
Published: (2017) -
Effectiveness of radiation synovectomy with samarium-153 particulate hydroxyapatite in rheumatoid arthritis patients with knee synovitis: a controlled randomized double-blind trial
by: Santos,Marla Francisca dos, et al.
Published: (2009) -
COMPARED EFFICACY OF INTRA-ARTICULAR INJECTION OF METHYLPREDNISOLONE AND TRIAMCINOLONE
by: BUYUK,ABDUL FETTAH, et al.
Published: (2017) -
Intra-articular injection in patients with juvenile idiopathic arthritis: factors associated with a good response
by: Cunha,Ana Luiza Garcia, et al.
Published: (2016)