A facile and practical p-Toluenesulfonic acid catalyzed route to dicoumarols containing an Aroyl group
New and known dicoumarols may be efficiently synthesized employing p-toluenesulfonic acid (p-TSA) as a solid acid catalyst from the reaction of 4-hydroxycoumarin with aryl glyoxal in water. This method offers direct access to structurally diverse coumarin derivatives in moderate to good yields (up to 65%). A total of five new compounds were synthesized.
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Main Authors: | , , , |
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Format: | Digital revista |
Language: | English |
Published: |
The South African Chemical Institute
2015
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Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502015000100008 |
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