Severe Darier's disease in a psychiatric patient

Abstract Darier’s disease is characterized by dense keratotic lesions in the seborrheic areas of the body such as scalp, forehead, nasolabial folds, trunk and inguinal region. It is a rare genodermatosis, an autosomal dominant inherited disease that may be associated with neuropsichiatric disorders. It is caused by ATPA2 gene mutation, presenting cutaneous and dermatologic expressions. Psychiatric symptoms are depression, suicidal attempts, and bipolar affective disorder. We report a case of Darier’s disease in a 48-year-old female patient presenting severe cutaneous and psychiatric manifestations.

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Bibliographic Details
Main Authors: Yang,Jeane Jeong Hoon, Lopes,Roberta Simão, Pereira,Medéia Carolina Fernandes, Tebcherani,Antonio Jose, Pires,Mário Cezar
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700066
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