Vitamin D serum levels and peripheral arterial disease among southern Brazilian adults
SUMMARY OBJECTIVE To investigate the association between low serum vitamin D levels and peripheral arterial disease (PAD). METHODS A cross-sectional study with a consecutive sample of 133 individuals from Caxias do Sul, Brasil. We considered PAD patients those with an ankle-brachial index (ABI) ≤ 0.90 or with arterial revascularization. Vitamin D serum level was categorized as sufficient (≥30 ng/mL), insufficient (>20 to 29 ng/mL), and deficient (<20 ng/mL). Prevalence ratios (RP) were calculated through Poisson regression. RESULTS The prevalence of PAD was 50.7% (95% CI 42-59). After adjustment for potential PAD risk factors, RP were 1.08 (95% CI 0.66-1.76) for insufficient serum level and 1.57 (95% CI 0.96-2.57) for deficient vitamin D serum level; (p for trend = 0.020). CONCLUSION Vitamin D serum levels showed an inverse and significant dose-response relationship with PAD.
Main Authors: | Bonatto,Simone, Paniz,Vera Maria Vieira, Dutra,Clandio de Freitas, Henn,Ruth Liane |
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Format: | Digital revista |
Language: | English |
Published: |
Associação Médica Brasileira
2020
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000300268 |
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