Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.
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Associação Médica Brasileira
2016
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oai:scielo:S0104-423020160012000102016-12-01Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendationsDuarte,Fernando BarrosoPrado,Benedito de Pina AlmeidaVieira,Garles Miller MatiasCosta,Luciano J. Hematopoietic stem cell mobilization Autologous transplantation Plerixafor G-CSF SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.62 suppl.1 20162016-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010en10.1590/1806-9282.62.suppl1.10 |
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Duarte,Fernando Barroso Prado,Benedito de Pina Almeida Vieira,Garles Miller Matias Costa,Luciano J. |
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Duarte,Fernando Barroso Prado,Benedito de Pina Almeida Vieira,Garles Miller Matias Costa,Luciano J. Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
author_facet |
Duarte,Fernando Barroso Prado,Benedito de Pina Almeida Vieira,Garles Miller Matias Costa,Luciano J. |
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Duarte,Fernando Barroso |
title |
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
title_short |
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
title_full |
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
title_fullStr |
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
title_full_unstemmed |
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
title_sort |
mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations |
description |
SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources. |
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Associação Médica Brasileira |
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2016 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010 |
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