Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations

SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.

Saved in:
Bibliographic Details
Main Authors: Duarte,Fernando Barroso, Prado,Benedito de Pina Almeida, Vieira,Garles Miller Matias, Costa,Luciano J.
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S0104-42302016001200010
record_format ojs
spelling oai:scielo:S0104-423020160012000102016-12-01Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendationsDuarte,Fernando BarrosoPrado,Benedito de Pina AlmeidaVieira,Garles Miller MatiasCosta,Luciano J. Hematopoietic stem cell mobilization Autologous transplantation Plerixafor G-CSF SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.info:eu-repo/semantics/openAccessAssociação Médica BrasileiraRevista da Associação Médica Brasileira v.62 suppl.1 20162016-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010en10.1590/1806-9282.62.suppl1.10
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Duarte,Fernando Barroso
Prado,Benedito de Pina Almeida
Vieira,Garles Miller Matias
Costa,Luciano J.
spellingShingle Duarte,Fernando Barroso
Prado,Benedito de Pina Almeida
Vieira,Garles Miller Matias
Costa,Luciano J.
Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
author_facet Duarte,Fernando Barroso
Prado,Benedito de Pina Almeida
Vieira,Garles Miller Matias
Costa,Luciano J.
author_sort Duarte,Fernando Barroso
title Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_short Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_full Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_fullStr Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_full_unstemmed Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_sort mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
description SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.
publisher Associação Médica Brasileira
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010
work_keys_str_mv AT duartefernandobarroso mobilizationofhematopoieticprogenitorcellsforautologoustransportationconsensusrecommendations
AT pradobeneditodepinaalmeida mobilizationofhematopoieticprogenitorcellsforautologoustransportationconsensusrecommendations
AT vieiragarlesmillermatias mobilizationofhematopoieticprogenitorcellsforautologoustransportationconsensusrecommendations
AT costalucianoj mobilizationofhematopoieticprogenitorcellsforautologoustransportationconsensusrecommendations
_version_ 1756409956911808512