Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil

Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil

Pluronic® F127 nanoparticles were loaded with citronella essential oil (CEO) and then covered with chitosan-sodium alginate polyelectrolyte complex (PEC). The system was characterized according to size, zeta potential and stability over time. Dynamic light scattering (DLS) in different proportions of water/ethanol as a dispersive medium was important in confirming that PEC covered the F127 nanoparticles. Infrared spectroscopy also indicated interaction of F127 with PEC. The nanoparticle size evaluated by transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) corroborated the value observed in DLS (hydrodynamic radius (RH) range of 100-200 nm). Encapsulation efficiency of 80% for CEO was determined by UV-Vis spectroscopy. The release profile of the CEO was evaluated in phosphate buffer saline (PBS) containing 20% of ethanol and in simulated sweat fluid, achieving 74 and 81%, respectively. The releasing mechanism fitted the Korsmeyer-Peppas mathematical model, indicating Fickian diffusion behavior for both studied media.

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Main Authors: Sanches,Mariele P., Gross,Idejan P., Saatkamp,Rodrigo H., Parize,Alexandre L., Soldi,Valdir
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000400803
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spelling oai:scielo:S0103-505320200004008032020-03-19Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential OilSanches,Mariele P.Gross,Idejan P.Saatkamp,Rodrigo H.Parize,Alexandre L.Soldi,Valdir citronella essential oil encapsulation efficiency nanoparticles polyelectrolyte complex Pluronic® F127 nanoparticles were loaded with citronella essential oil (CEO) and then covered with chitosan-sodium alginate polyelectrolyte complex (PEC). The system was characterized according to size, zeta potential and stability over time. Dynamic light scattering (DLS) in different proportions of water/ethanol as a dispersive medium was important in confirming that PEC covered the F127 nanoparticles. Infrared spectroscopy also indicated interaction of F127 with PEC. The nanoparticle size evaluated by transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) corroborated the value observed in DLS (hydrodynamic radius (RH) range of 100-200 nm). Encapsulation efficiency of 80% for CEO was determined by UV-Vis spectroscopy. The release profile of the CEO was evaluated in phosphate buffer saline (PBS) containing 20% of ethanol and in simulated sweat fluid, achieving 74 and 81%, respectively. The releasing mechanism fitted the Korsmeyer-Peppas mathematical model, indicating Fickian diffusion behavior for both studied media.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society v.31 n.4 20202020-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000400803en10.21577/0103-5053.20190244
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Sanches,Mariele P.
Gross,Idejan P.
Saatkamp,Rodrigo H.
Parize,Alexandre L.
Soldi,Valdir
spellingShingle Sanches,Mariele P.
Gross,Idejan P.
Saatkamp,Rodrigo H.
Parize,Alexandre L.
Soldi,Valdir
Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil
author_facet Sanches,Mariele P.
Gross,Idejan P.
Saatkamp,Rodrigo H.
Parize,Alexandre L.
Soldi,Valdir
author_sort Sanches,Mariele P.
title Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil
title_short Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil
title_full Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil
title_fullStr Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil
title_full_unstemmed Chitosan-Sodium Alginate Polyelectrolyte Complex Coating Pluronic® F127 Nanoparticles Loaded with Citronella Essential Oil
title_sort chitosan-sodium alginate polyelectrolyte complex coating pluronic® f127 nanoparticles loaded with citronella essential oil
description Pluronic® F127 nanoparticles were loaded with citronella essential oil (CEO) and then covered with chitosan-sodium alginate polyelectrolyte complex (PEC). The system was characterized according to size, zeta potential and stability over time. Dynamic light scattering (DLS) in different proportions of water/ethanol as a dispersive medium was important in confirming that PEC covered the F127 nanoparticles. Infrared spectroscopy also indicated interaction of F127 with PEC. The nanoparticle size evaluated by transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) corroborated the value observed in DLS (hydrodynamic radius (RH) range of 100-200 nm). Encapsulation efficiency of 80% for CEO was determined by UV-Vis spectroscopy. The release profile of the CEO was evaluated in phosphate buffer saline (PBS) containing 20% of ethanol and in simulated sweat fluid, achieving 74 and 81%, respectively. The releasing mechanism fitted the Korsmeyer-Peppas mathematical model, indicating Fickian diffusion behavior for both studied media.
publisher Sociedade Brasileira de Química
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000400803
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AT saatkamprodrigoh chitosansodiumalginatepolyelectrolytecomplexcoatingpluronicf127nanoparticlesloadedwithcitronellaessentialoil
AT parizealexandrel chitosansodiumalginatepolyelectrolytecomplexcoatingpluronicf127nanoparticlesloadedwithcitronellaessentialoil
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