Synthesis of platinum complexes from N-benzyl ethylenediamine derivatives
N-benzylethylenediamine derivatives have been prepared in good yields using methodology diferent than that described in the literature. ¹H and 13C NMR spectra were used to characterize those compounds. Nine new platinum(II) complexes, analogs of cisplatin and carboplatin, containing these ligands have been prepared and characterized. Preliminary in vitro tests against buccal human carcinoma cell lines (KB cells) showed that the complexes are cytotoxic.
Saved in:
Main Authors: | Almeida,Mauro V. de, Cesar,Eloi T., Felício,Emanoel de C. A., Fontes,Ana Paula S., Robert-Gero,Malka |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2000
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200009 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis and characterization of platinum(II) complexes from trifluoromethyl phenylenediamine, picoline and N-benzyl ethylenediamine derivatives
by: Almeida,Mauro V. de, et al.
Published: (2006) -
Synthesis of novel 6-(substituted benzyl)imidazo[2,1-b][1,3]thiazole catalyzed by polystyrene-supported palladium(ii) ethylenediamine complex
by: Bakherad,Mohammad, et al.
Published: (2009) -
Synthesis and evaluation of platinum complexes with potential antitumor activity
by: Freire,Rachel Lima Marcelino, et al.
Published: (2017) -
SYNTHESIS OF N-(HALOGENATED) BENZYL ANALOGS OF SUPERPOTENT SEROTONIN LIGANDS
by: TIRAPEGUI,CRISTIAN, et al.
Published: (2014) -
Stereoselective synthesis of tris[Di-m-hydroxy-bis-(ethylenediamine)] tetracobalt(III)
by: Parada A,José, et al.
Published: (2005)