HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS

ABSTRACT Objective: To assess the frequency of the hypertriglyceridemic waist phenotype and its associated factors in children and adolescents with type 1 diabetes mellitus. Methods: This is an observational analytical study with individuals with type 1 diabetes mellitus, aged 5 to 18 years, of both genders, followed in a university hospital in the Brazilian Northeast. Weight, height, and waist circumference were measured, and the lipid profile and glycated hemoglobin were analyzed. The hypertriglyceridemic waist phenotype was defined by the simultaneous presence of increased waist circumference (≥90th percentile for age and gender) and elevated serum triglyceride levels (≥75 mg/dL for children and ≥90 mg/dL for adolescents). We also investigated the family history of cardiovascular diseases and diabetes, as well as sociodemographic and behavioral variables. In the statistical inference tests, the proportions were compared by Pearson’s chi-square test ­and/­or Fisher’s exact test, being significant p<0.05. Results: A total of 102 patients were evaluated, most of them females (54.9%) and adolescents (66.7%). The frequency of hypertriglyceridemic waist was 23.5%, which was associated with females (p=0.043), overweight (p=0.023), hypercholesterolemia (p=0.002), high LDL (p=0.001), and borderline VLDL (<0.001). Conclusions: The frequency of the hypertriglyceridemic waist phenotype was associated with females, atherogenic lipid profile, and overweight, indicating the importance of the nutritional monitoring of this population, aiming at reducing future cardiovascular diseases.

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Main Authors: Silva,Lílian Caroline de Souza e, Silva,Skalyt Lee Barbosa e, Oliveira,Ávilla Monalisa Silva de, Araujo,Jacqueline Rosangela de, Arruda,Ilma Kruze Grande de, Maio,Regiane, Lemos,Maria da Conceição Chaves de
Format: Digital revista
Language:English
Published: Sociedade de Pediatria de São Paulo 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822020000100434
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spelling oai:scielo:S0103-058220200001004342020-11-03HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUSSilva,Lílian Caroline de Souza eSilva,Skalyt Lee Barbosa eOliveira,Ávilla Monalisa Silva deAraujo,Jacqueline Rosangela deArruda,Ilma Kruze Grande deMaio,RegianeLemos,Maria da Conceição Chaves de Hypertriglyceridemic waist Type 1 diabetes mellitus Children ABSTRACT Objective: To assess the frequency of the hypertriglyceridemic waist phenotype and its associated factors in children and adolescents with type 1 diabetes mellitus. Methods: This is an observational analytical study with individuals with type 1 diabetes mellitus, aged 5 to 18 years, of both genders, followed in a university hospital in the Brazilian Northeast. Weight, height, and waist circumference were measured, and the lipid profile and glycated hemoglobin were analyzed. The hypertriglyceridemic waist phenotype was defined by the simultaneous presence of increased waist circumference (≥90th percentile for age and gender) and elevated serum triglyceride levels (≥75 mg/dL for children and ≥90 mg/dL for adolescents). We also investigated the family history of cardiovascular diseases and diabetes, as well as sociodemographic and behavioral variables. In the statistical inference tests, the proportions were compared by Pearson’s chi-square test ­and/­or Fisher’s exact test, being significant p<0.05. Results: A total of 102 patients were evaluated, most of them females (54.9%) and adolescents (66.7%). The frequency of hypertriglyceridemic waist was 23.5%, which was associated with females (p=0.043), overweight (p=0.023), hypercholesterolemia (p=0.002), high LDL (p=0.001), and borderline VLDL (<0.001). Conclusions: The frequency of the hypertriglyceridemic waist phenotype was associated with females, atherogenic lipid profile, and overweight, indicating the importance of the nutritional monitoring of this population, aiming at reducing future cardiovascular diseases.info:eu-repo/semantics/openAccessSociedade de Pediatria de São PauloRevista Paulista de Pediatria v.38 20202020-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822020000100434en10.1590/1984-0462/2020/38/2019073
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language English
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author Silva,Lílian Caroline de Souza e
Silva,Skalyt Lee Barbosa e
Oliveira,Ávilla Monalisa Silva de
Araujo,Jacqueline Rosangela de
Arruda,Ilma Kruze Grande de
Maio,Regiane
Lemos,Maria da Conceição Chaves de
spellingShingle Silva,Lílian Caroline de Souza e
Silva,Skalyt Lee Barbosa e
Oliveira,Ávilla Monalisa Silva de
Araujo,Jacqueline Rosangela de
Arruda,Ilma Kruze Grande de
Maio,Regiane
Lemos,Maria da Conceição Chaves de
HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
author_facet Silva,Lílian Caroline de Souza e
Silva,Skalyt Lee Barbosa e
Oliveira,Ávilla Monalisa Silva de
Araujo,Jacqueline Rosangela de
Arruda,Ilma Kruze Grande de
Maio,Regiane
Lemos,Maria da Conceição Chaves de
author_sort Silva,Lílian Caroline de Souza e
title HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
title_short HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
title_full HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
title_fullStr HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
title_full_unstemmed HYPERTRIGLYCERIDEMIC WAIST AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS
title_sort hypertriglyceridemic waist and associated factors in children and adolescents with type 1 diabetes mellitus
description ABSTRACT Objective: To assess the frequency of the hypertriglyceridemic waist phenotype and its associated factors in children and adolescents with type 1 diabetes mellitus. Methods: This is an observational analytical study with individuals with type 1 diabetes mellitus, aged 5 to 18 years, of both genders, followed in a university hospital in the Brazilian Northeast. Weight, height, and waist circumference were measured, and the lipid profile and glycated hemoglobin were analyzed. The hypertriglyceridemic waist phenotype was defined by the simultaneous presence of increased waist circumference (≥90th percentile for age and gender) and elevated serum triglyceride levels (≥75 mg/dL for children and ≥90 mg/dL for adolescents). We also investigated the family history of cardiovascular diseases and diabetes, as well as sociodemographic and behavioral variables. In the statistical inference tests, the proportions were compared by Pearson’s chi-square test ­and/­or Fisher’s exact test, being significant p<0.05. Results: A total of 102 patients were evaluated, most of them females (54.9%) and adolescents (66.7%). The frequency of hypertriglyceridemic waist was 23.5%, which was associated with females (p=0.043), overweight (p=0.023), hypercholesterolemia (p=0.002), high LDL (p=0.001), and borderline VLDL (<0.001). Conclusions: The frequency of the hypertriglyceridemic waist phenotype was associated with females, atherogenic lipid profile, and overweight, indicating the importance of the nutritional monitoring of this population, aiming at reducing future cardiovascular diseases.
publisher Sociedade de Pediatria de São Paulo
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822020000100434
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