Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula
PURPOSE:To investigate the hemodynamic and ventilatory changes associated with the creation of an experimental bronchopleural fistula (BPF) treated by mechanical ventilation and thoracic drainage with or without a water seal.METHODS :Six large white pigs weighing 25 kg each which, after general anesthesia, underwent endotracheal intubation (6mm), and mechanically ventilation. Through a left thoracotomy, a resection of the lingula was performed in order to create a BPF with an output exceeding 50% of the inspired volume. The chest cavity was closed and drained into the water sealed system for initial observation of the high output BPF.RESULTS:Significant reduction in BPF output and PaCO2 was related after insertion of a water-sealed thoracic drain, p< 0.05.CONCLUSION: Insertion of a water-sealed thoracic drain resulted in reduction in bronchopleural fistula output and better CO2 clearance without any drop in cardiac output or significant changes in mean arterial pressure.
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2015
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oai:scielo:S0102-865020150001000012015-10-08Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistulaOliveira,Douglas Guimaraes deToneloto,Maria Gabriela CavicchiaMoreira,Marcos MelloBustorff-Silva,Joaquim MurraySouza,Gabriel Franco deMartins,Luiz ClaudioKosour,CarolinaDragosavac,DesankaFalcão,Antonio Luis Eiras Respiratory Tract Fistula Respiration, Artificial Models, Animal Swine PURPOSE:To investigate the hemodynamic and ventilatory changes associated with the creation of an experimental bronchopleural fistula (BPF) treated by mechanical ventilation and thoracic drainage with or without a water seal.METHODS :Six large white pigs weighing 25 kg each which, after general anesthesia, underwent endotracheal intubation (6mm), and mechanically ventilation. Through a left thoracotomy, a resection of the lingula was performed in order to create a BPF with an output exceeding 50% of the inspired volume. The chest cavity was closed and drained into the water sealed system for initial observation of the high output BPF.RESULTS:Significant reduction in BPF output and PaCO2 was related after insertion of a water-sealed thoracic drain, p< 0.05.CONCLUSION: Insertion of a water-sealed thoracic drain resulted in reduction in bronchopleural fistula output and better CO2 clearance without any drop in cardiac output or significant changes in mean arterial pressure.info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.30 n.1 20152015-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000100001en10.1590/S0102-86502015001000001 |
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Oliveira,Douglas Guimaraes de Toneloto,Maria Gabriela Cavicchia Moreira,Marcos Mello Bustorff-Silva,Joaquim Murray Souza,Gabriel Franco de Martins,Luiz Claudio Kosour,Carolina Dragosavac,Desanka Falcão,Antonio Luis Eiras |
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Oliveira,Douglas Guimaraes de Toneloto,Maria Gabriela Cavicchia Moreira,Marcos Mello Bustorff-Silva,Joaquim Murray Souza,Gabriel Franco de Martins,Luiz Claudio Kosour,Carolina Dragosavac,Desanka Falcão,Antonio Luis Eiras Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
author_facet |
Oliveira,Douglas Guimaraes de Toneloto,Maria Gabriela Cavicchia Moreira,Marcos Mello Bustorff-Silva,Joaquim Murray Souza,Gabriel Franco de Martins,Luiz Claudio Kosour,Carolina Dragosavac,Desanka Falcão,Antonio Luis Eiras |
author_sort |
Oliveira,Douglas Guimaraes de |
title |
Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
title_short |
Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
title_full |
Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
title_fullStr |
Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
title_full_unstemmed |
Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
title_sort |
hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula |
description |
PURPOSE:To investigate the hemodynamic and ventilatory changes associated with the creation of an experimental bronchopleural fistula (BPF) treated by mechanical ventilation and thoracic drainage with or without a water seal.METHODS :Six large white pigs weighing 25 kg each which, after general anesthesia, underwent endotracheal intubation (6mm), and mechanically ventilation. Through a left thoracotomy, a resection of the lingula was performed in order to create a BPF with an output exceeding 50% of the inspired volume. The chest cavity was closed and drained into the water sealed system for initial observation of the high output BPF.RESULTS:Significant reduction in BPF output and PaCO2 was related after insertion of a water-sealed thoracic drain, p< 0.05.CONCLUSION: Insertion of a water-sealed thoracic drain resulted in reduction in bronchopleural fistula output and better CO2 clearance without any drop in cardiac output or significant changes in mean arterial pressure. |
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
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2015 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000100001 |
work_keys_str_mv |
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