Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.
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Sociedade Brasileira de Nefrologia
2016
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oai:scielo:S0101-280020160003003342016-10-04Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in BrazilMota,Luana SorianoOliveira,Claudia Maria Costa dePinheiro Junior,Francisco Martho LealSantos,Larissa Costa de OliveiraNóbrega,Danilo GonçalvesFernandes,Paula FBCCosta,Alda Angélica de MeloSilva,Sônia Leite da delayed graft function graft rate kidney transplantation survival rate. Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.info:eu-repo/semantics/openAccessSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology v.38 n.3 20162016-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334en10.5935/0101-2800.20160051 |
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Mota,Luana Soriano Oliveira,Claudia Maria Costa de Pinheiro Junior,Francisco Martho Leal Santos,Larissa Costa de Oliveira Nóbrega,Danilo Gonçalves Fernandes,Paula FBC Costa,Alda Angélica de Melo Silva,Sônia Leite da |
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Mota,Luana Soriano Oliveira,Claudia Maria Costa de Pinheiro Junior,Francisco Martho Leal Santos,Larissa Costa de Oliveira Nóbrega,Danilo Gonçalves Fernandes,Paula FBC Costa,Alda Angélica de Melo Silva,Sônia Leite da Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
author_facet |
Mota,Luana Soriano Oliveira,Claudia Maria Costa de Pinheiro Junior,Francisco Martho Leal Santos,Larissa Costa de Oliveira Nóbrega,Danilo Gonçalves Fernandes,Paula FBC Costa,Alda Angélica de Melo Silva,Sônia Leite da |
author_sort |
Mota,Luana Soriano |
title |
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
title_short |
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
title_full |
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
title_fullStr |
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
title_full_unstemmed |
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil |
title_sort |
comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in brazil |
description |
Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD. |
publisher |
Sociedade Brasileira de Nefrologia |
publishDate |
2016 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334 |
work_keys_str_mv |
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