Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil

Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.

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Main Authors: Mota,Luana Soriano, Oliveira,Claudia Maria Costa de, Pinheiro Junior,Francisco Martho Leal, Santos,Larissa Costa de Oliveira, Nóbrega,Danilo Gonçalves, Fernandes,Paula FBC, Costa,Alda Angélica de Melo, Silva,Sônia Leite da
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Nefrologia 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334
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spelling oai:scielo:S0101-280020160003003342016-10-04Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in BrazilMota,Luana SorianoOliveira,Claudia Maria Costa dePinheiro Junior,Francisco Martho LealSantos,Larissa Costa de OliveiraNóbrega,Danilo GonçalvesFernandes,Paula FBCCosta,Alda Angélica de MeloSilva,Sônia Leite da delayed graft function graft rate kidney transplantation survival rate. Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.info:eu-repo/semantics/openAccessSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology v.38 n.3 20162016-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334en10.5935/0101-2800.20160051
institution SCIELO
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Mota,Luana Soriano
Oliveira,Claudia Maria Costa de
Pinheiro Junior,Francisco Martho Leal
Santos,Larissa Costa de Oliveira
Nóbrega,Danilo Gonçalves
Fernandes,Paula FBC
Costa,Alda Angélica de Melo
Silva,Sônia Leite da
spellingShingle Mota,Luana Soriano
Oliveira,Claudia Maria Costa de
Pinheiro Junior,Francisco Martho Leal
Santos,Larissa Costa de Oliveira
Nóbrega,Danilo Gonçalves
Fernandes,Paula FBC
Costa,Alda Angélica de Melo
Silva,Sônia Leite da
Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
author_facet Mota,Luana Soriano
Oliveira,Claudia Maria Costa de
Pinheiro Junior,Francisco Martho Leal
Santos,Larissa Costa de Oliveira
Nóbrega,Danilo Gonçalves
Fernandes,Paula FBC
Costa,Alda Angélica de Melo
Silva,Sônia Leite da
author_sort Mota,Luana Soriano
title Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
title_short Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
title_full Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
title_fullStr Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
title_full_unstemmed Comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in Brazil
title_sort comparative study between kidney transplantation with deceased donor expanded criteria and donor standard criteria in a single center in brazil
description Abstract Introduction: Kidney transplants with expanded criteria donor have been associated with improved patient survival compared to those who remain on dialysis. Objective: To compare renal function and survival of the kidney graft of deceased donor with expanded criteria and standard criteria over a year in a single transplant center. Methods: 255 kidney transplant recipients with deceased donor were included in the study between the years 2011 to 2013 and they were separated into two groups according to the type of donor (expanded criteria donor - ECD - and standard criteria donor - SCD). Results: 231 deceased donor transplants (90.6%) were performed with standard criteria donor (SCD) and 24 (9.4%) with expanded criteria donor (ECD). There was no difference in the prevalence of delayed graft function - DGF - (62.9% vs. 70.8%; p = 0.44). Expanded criteria donor group had lower glomerular filtration rate (GFR) at the end of the 1st year (56.8 ± 26.9 vs. 76.9 ± 23.7; p = 0.001). Patient survival was significantly lower in the ECD group, but the graft survival was not different after death-censored analysis. Conclusion: The ECD group was associated with significantly lower levels of GFR during the first year of transplant and a lower patient survival at the 1st year when compared to the SCD.
publisher Sociedade Brasileira de Nefrologia
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002016000300334
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