Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units

ABSTRACT Objective: To assess the capacity of Charlson, SAPS 3 and SOFA scores to predict acute kidney injury, need for dialysis, and death in intensive care unit patients. Method: Prospective cohort, with 432 individuals admitted to four intensive care units. Clinical characteristics at admission, severity profile, and intensity of care were analyzed using association and correlation tests. The scores sensitivity and specificity were assessed using the ROC curve. Results: The results show that patients with acute kidney injury were older (65[27] years vs. 60[25] years, p = 0.019) and mostly are from the emergency department (57.9% vs. 38.0 %, p < 0.001), when compared to those in the group without acute kidney injury. For dialysis prediction, the results of SAPS 3 and SOFA were AUC: 0.590; 95%CI: 0.507–0.674; p-value: 0.032 and AUC: 0.667; 95%CI: 0.591–0.743; p-value: 0.000, respectively. All scores performed well for death. Conclusion: The prognostic scores showed good capacity to predict acute kidney injury, dialysis, and death. Charlson Comorbidity Index showed good predictive capacity for acute kidney injury and death; however, it did not perform well for the need for dialysis.

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Main Authors: Vasconcelos,Geferson Messias Teles, Magro,Marcia Cristina da Silva, da Fonseca,Cassiane Dezoti, Oliveira,Jussiely Cunha, Santana-Santos,Eduesley
Format: Digital revista
Language:English
Published: Universidade de São Paulo, Escola de Enfermagem 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342021000100562
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spelling oai:scielo:S0080-623420210001005622021-09-29Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care unitsVasconcelos,Geferson Messias TelesMagro,Marcia Cristina da Silvada Fonseca,Cassiane DezotiOliveira,Jussiely CunhaSantana-Santos,Eduesley Acute Kidney Injury Intensive Care Units Dialysis Death Simplified Acute Physiology Score Organ Dysfunction Scores ABSTRACT Objective: To assess the capacity of Charlson, SAPS 3 and SOFA scores to predict acute kidney injury, need for dialysis, and death in intensive care unit patients. Method: Prospective cohort, with 432 individuals admitted to four intensive care units. Clinical characteristics at admission, severity profile, and intensity of care were analyzed using association and correlation tests. The scores sensitivity and specificity were assessed using the ROC curve. Results: The results show that patients with acute kidney injury were older (65[27] years vs. 60[25] years, p = 0.019) and mostly are from the emergency department (57.9% vs. 38.0 %, p < 0.001), when compared to those in the group without acute kidney injury. For dialysis prediction, the results of SAPS 3 and SOFA were AUC: 0.590; 95%CI: 0.507–0.674; p-value: 0.032 and AUC: 0.667; 95%CI: 0.591–0.743; p-value: 0.000, respectively. All scores performed well for death. Conclusion: The prognostic scores showed good capacity to predict acute kidney injury, dialysis, and death. Charlson Comorbidity Index showed good predictive capacity for acute kidney injury and death; however, it did not perform well for the need for dialysis.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Escola de EnfermagemRevista da Escola de Enfermagem da USP v.55 20212021-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342021000100562en10.1590/1980-220x-reeusp-2021-0071
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libraryname SciELO
language English
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author Vasconcelos,Geferson Messias Teles
Magro,Marcia Cristina da Silva
da Fonseca,Cassiane Dezoti
Oliveira,Jussiely Cunha
Santana-Santos,Eduesley
spellingShingle Vasconcelos,Geferson Messias Teles
Magro,Marcia Cristina da Silva
da Fonseca,Cassiane Dezoti
Oliveira,Jussiely Cunha
Santana-Santos,Eduesley
Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
author_facet Vasconcelos,Geferson Messias Teles
Magro,Marcia Cristina da Silva
da Fonseca,Cassiane Dezoti
Oliveira,Jussiely Cunha
Santana-Santos,Eduesley
author_sort Vasconcelos,Geferson Messias Teles
title Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
title_short Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
title_full Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
title_fullStr Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
title_full_unstemmed Predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
title_sort predictive capacity of prognostic scores for kidney injury, dialysis, and death in intensive care units
description ABSTRACT Objective: To assess the capacity of Charlson, SAPS 3 and SOFA scores to predict acute kidney injury, need for dialysis, and death in intensive care unit patients. Method: Prospective cohort, with 432 individuals admitted to four intensive care units. Clinical characteristics at admission, severity profile, and intensity of care were analyzed using association and correlation tests. The scores sensitivity and specificity were assessed using the ROC curve. Results: The results show that patients with acute kidney injury were older (65[27] years vs. 60[25] years, p = 0.019) and mostly are from the emergency department (57.9% vs. 38.0 %, p < 0.001), when compared to those in the group without acute kidney injury. For dialysis prediction, the results of SAPS 3 and SOFA were AUC: 0.590; 95%CI: 0.507–0.674; p-value: 0.032 and AUC: 0.667; 95%CI: 0.591–0.743; p-value: 0.000, respectively. All scores performed well for death. Conclusion: The prognostic scores showed good capacity to predict acute kidney injury, dialysis, and death. Charlson Comorbidity Index showed good predictive capacity for acute kidney injury and death; however, it did not perform well for the need for dialysis.
publisher Universidade de São Paulo, Escola de Enfermagem
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342021000100562
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