Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.

Abstract: INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. RESULTS Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. CONCLUSIONS Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas.

Bibliographic Details

Main Authors:	Batista,Luís Fábio da Silva, Matta,Vânia Lúcia Ribeiro da, Tomokane,Thaise Yumie, Pacheco,Acácio Duarte, Silveira,Fernando Tobias, Rossi,Claudio Nazaretian, Marcondes,Mary, Laurenti,Márcia Dalastra
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Medicina Tropical - SBMT 2016
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000300361
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