Description of a possible clonal expansion of Plasmodium vivax in Manaus - Amazonas - Brazil

Atypical P. vivax cases reported in Manaus municipality led us to detect a genetic isolate of P. vivax. Variable regions of SSUrRNA were examined from the initial time of infection and in the two recrudescences/relapses from a patient exhibiting chloroquine and primaquine resistance. A unique isolate, found at all stages of infection, suggests the presence of a clonal expansion.

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Bibliographic Details
Main Authors: Alecrim,Maria das Graças Costa, Alecrim,Wilson Duarte, Macêdo,Vanize, Korves,Caroline T., Roberts,Donald R., Li,Jun, Sullivan,Margery, McCutchan,Thomas F.
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 1999
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821999000300014
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