LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES
Leprosy is a chronic disease caused by Mycobacterium leprae, highly incapacitating, and with systemic involvement in some cases. Renal involvement has been reported in all forms of the disease, and it is more frequent in multibacillary forms. The clinical presentation is variable and is determined by the host immunologic system reaction to the bacilli. During the course of the disease there are the so called reactional states, in which the immune system reacts against the bacilli, exacerbating the clinical manifestations. Different renal lesions have been described in leprosy, including acute and chronic glomerulonephritis, interstitial nephritis, secondary amyloidosis and pyelonephritis. The exact mechanism that leads to glomerulonephritis in leprosy is not completely understood. Leprosy treatment includes rifampicin, dapsone and clofazimine. Prednisone and non-steroidal anti-inflammatory drugs may be used to control acute immunological episodes.
Main Authors: | , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Instituto de Medicina Tropical de São Paulo
2015
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652015000100015 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S0036-46652015000100015 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S0036-466520150001000152015-02-27LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURESSilva Junior,Geraldo Bezerra daDaher,Elizabeth De FrancescoPires NETO,Roberto da JustaPereira,Eanes Delgado BarrosMeneses,Gdayllon CavalcanteAraújo,Sônia Maria Holanda AlmeidaBarros,Elvino José Guardão Leprosy Hansen disease Kidney dysfunction Chronic kidney disease Glomerulonephritis Leprosy is a chronic disease caused by Mycobacterium leprae, highly incapacitating, and with systemic involvement in some cases. Renal involvement has been reported in all forms of the disease, and it is more frequent in multibacillary forms. The clinical presentation is variable and is determined by the host immunologic system reaction to the bacilli. During the course of the disease there are the so called reactional states, in which the immune system reacts against the bacilli, exacerbating the clinical manifestations. Different renal lesions have been described in leprosy, including acute and chronic glomerulonephritis, interstitial nephritis, secondary amyloidosis and pyelonephritis. The exact mechanism that leads to glomerulonephritis in leprosy is not completely understood. Leprosy treatment includes rifampicin, dapsone and clofazimine. Prednisone and non-steroidal anti-inflammatory drugs may be used to control acute immunological episodes.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.57 n.1 20152015-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652015000100015en10.1590/S0036-46652015000100002 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Silva Junior,Geraldo Bezerra da Daher,Elizabeth De Francesco Pires NETO,Roberto da Justa Pereira,Eanes Delgado Barros Meneses,Gdayllon Cavalcante Araújo,Sônia Maria Holanda Almeida Barros,Elvino José Guardão |
spellingShingle |
Silva Junior,Geraldo Bezerra da Daher,Elizabeth De Francesco Pires NETO,Roberto da Justa Pereira,Eanes Delgado Barros Meneses,Gdayllon Cavalcante Araújo,Sônia Maria Holanda Almeida Barros,Elvino José Guardão LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES |
author_facet |
Silva Junior,Geraldo Bezerra da Daher,Elizabeth De Francesco Pires NETO,Roberto da Justa Pereira,Eanes Delgado Barros Meneses,Gdayllon Cavalcante Araújo,Sônia Maria Holanda Almeida Barros,Elvino José Guardão |
author_sort |
Silva Junior,Geraldo Bezerra da |
title |
LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES |
title_short |
LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES |
title_full |
LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES |
title_fullStr |
LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES |
title_full_unstemmed |
LEPROSY NEPHROPATHY: A REVIEW OF CLINICAL AND HISTOPATHOLOGICAL FEATURES |
title_sort |
leprosy nephropathy: a review of clinical and histopathological features |
description |
Leprosy is a chronic disease caused by Mycobacterium leprae, highly incapacitating, and with systemic involvement in some cases. Renal involvement has been reported in all forms of the disease, and it is more frequent in multibacillary forms. The clinical presentation is variable and is determined by the host immunologic system reaction to the bacilli. During the course of the disease there are the so called reactional states, in which the immune system reacts against the bacilli, exacerbating the clinical manifestations. Different renal lesions have been described in leprosy, including acute and chronic glomerulonephritis, interstitial nephritis, secondary amyloidosis and pyelonephritis. The exact mechanism that leads to glomerulonephritis in leprosy is not completely understood. Leprosy treatment includes rifampicin, dapsone and clofazimine. Prednisone and non-steroidal anti-inflammatory drugs may be used to control acute immunological episodes. |
publisher |
Instituto de Medicina Tropical de São Paulo |
publishDate |
2015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652015000100015 |
work_keys_str_mv |
AT silvajuniorgeraldobezerrada leprosynephropathyareviewofclinicalandhistopathologicalfeatures AT daherelizabethdefrancesco leprosynephropathyareviewofclinicalandhistopathologicalfeatures AT piresnetorobertodajusta leprosynephropathyareviewofclinicalandhistopathologicalfeatures AT pereiraeanesdelgadobarros leprosynephropathyareviewofclinicalandhistopathologicalfeatures AT menesesgdaylloncavalcante leprosynephropathyareviewofclinicalandhistopathologicalfeatures AT araujosoniamariaholandaalmeida leprosynephropathyareviewofclinicalandhistopathologicalfeatures AT barroselvinojoseguardao leprosynephropathyareviewofclinicalandhistopathologicalfeatures |
_version_ |
1756379893186166784 |