Linfangioleiomiomatosis pulmonar: Caso clínico

Lymphangioleiomyomatosis (LAM) is a rare interstitial lung disease, of unknown etiology, affecting almost exclusively women. Microscopically LAM consists of a diffuse proliferation of smooth muscle cells. LAM can occur without evidence of other diseases (sporadic LAM) or in conjunction with tuberous sclerosis complex (TSC). It presents with progressive breathlessness or with recurrent pneumothorax or chylothorax. We report a 33 year-old woman with a history of recurrent pneumothorax. Computed tomography (CT) scans showed numerous thin-walled cysts throughout the lungs, a characteristic finding in LAM. A pulmonary biopsy was compatible with the diagnosis and HMB-45 monoclonal antibodies were positive. Treatment with Sirolimus was started).

Bibliographic Details

Main Authors:	Silva O,Rafael, Puelma C,Felipe, Retamal P,Víctor, Rojas SM,Pedro, Cruzat C,Claudio, Reyes G,Cecilia
Format:	Digital revista
Language:	Spanish / Castilian
Published:	Sociedad Médica de Santiago 2009
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009001100010
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