Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code

Valente, Mauro Andrés; Malano, Francisco Mauricio; Pérez, Pedro Antonio

Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code

Trabajo presentado en el X Latin American Symposium on Nuclear Physics and Applications (X LASNPA), 1-6 diciembre 2013. Montevideo, Uruguay.

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Main Authors:	Valente, Mauro Andrés, Malano, Francisco Mauricio, Pérez, Pedro Antonio
Format:	article biblioteca
Language:	eng
Published:	2014
Subjects:	Medicina nuclear, Dosimetría, Nuclear medicine, Dosimetry, Alpha particles,
Online Access:	http://hdl.handle.net/11086/20130 https://doi.org/10.22323/1.194.0088
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id	dig-unc-ar-11086-20130
record_format	koha
spelling	dig-unc-ar-11086-201302022-10-13T11:07:08Z Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code Valente, Mauro Andrés Malano, Francisco Mauricio Pérez, Pedro Antonio Medicina nuclear Dosimetría Nuclear medicine Dosimetry Alpha particles Trabajo presentado en el X Latin American Symposium on Nuclear Physics and Applications (X LASNPA), 1-6 diciembre 2013. Montevideo, Uruguay. Nuclear medicine clinical practices for neoplasic disease diagnose and treatment are based on the incorporation of α, β and γ radiotracers and radiopharmaceuticals, which might be associated with potential damage. Thus, being necessary accurate dosimetry strategies. In vivo absorbed dose appears as an ideal solution. However, its implementation in clinics does not attain enough reliability. In this sense, different approaches were proposed for internal dosimetry calculations. This work presents a novel analytical-numerical approach for internal dosimetry purposes. Dedicated Monte Carlo simulations were performed by subroutines adapted from the FLUKA code. In-water EDK were evaluated at different photon energies and some typical γ-emitters radiopharmaceuticals; whereas DPK were obtained for both α- and β- emitters. Additionally, EDK and DPK were calculated for several biological tissues. publishedVersion Fil: Valente, Mauro Andrés. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Fil: Valente, Mauro Andrés. Consejo Nacional de Investigaciones Científicas y Técnica. Instituto de Física Enrique Gaviola; Argentina. Fil: Valente, Mauro Andrés. Universidad Nacional de Córdoba. Laboratorio de Investigación e Instrumentación en Física Aplicada a la Medicina e Imágenes por Rayos X; Argentina. Fil: Malano, Francisco Mauricio. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Fil: Malano, Francisco Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina. Fil: Malano, Francisco Mauricio. Universidad Nacional de Córdoba. Laboratorio de Investigación e Instrumentación en Física Aplicada a la Medicina e Imágenes por Rayos X; Argentina. Fil: Pérez, Pedro Antonio. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Fil: Pérez, Pedro Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina. Fil: Pérez, Pedro Antonio. Universidad Nacional de Córdoba. Laboratorio de Investigación e Instrumentación en Física Aplicada a la Medicina e Imágenes por Rayos X; Argentina. Física Atómica, Molecular y Química (física de átomos y moléculas incluyendo colisión, interacción con radiación, resonancia magnética, Moessbauer Efecto.) 2021-09-06T16:32:29Z 2021-09-06T16:32:29Z 2014 article Valente, M. A., Malano, F. M. y Pérez, P. A. (2014). Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code. Proceedings of Science, 1-6. https://doi.org/10.22323/1.194.0088 http://hdl.handle.net/11086/20130 https://doi.org/10.22323/1.194.0088 eng Attribution-NonCommercial-ShareAlike 1.0 Generic https://creativecommons.org/licenses/by-nc-sa/1.0/ Electrónico y/o Digital ISSN 1824-8039
institution	UNC AR
collection	DSpace
country	Argentina
countrycode	AR
component	Bibliográfico
access	En linea
databasecode	dig-unc-ar
tag	biblioteca
region	America del Sur
libraryname	Biblioteca 'Ing. Agrónomo Moisés Farber' de la Facultad de Ciencias Agropecuarias
language	eng
topic	Medicina nuclear Dosimetría Nuclear medicine Dosimetry Alpha particles Medicina nuclear Dosimetría Nuclear medicine Dosimetry Alpha particles
spellingShingle	Medicina nuclear Dosimetría Nuclear medicine Dosimetry Alpha particles Medicina nuclear Dosimetría Nuclear medicine Dosimetry Alpha particles Valente, Mauro Andrés Malano, Francisco Mauricio Pérez, Pedro Antonio Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code
description	Trabajo presentado en el X Latin American Symposium on Nuclear Physics and Applications (X LASNPA), 1-6 diciembre 2013. Montevideo, Uruguay.
format	article
topic_facet	Medicina nuclear Dosimetría Nuclear medicine Dosimetry Alpha particles
author	Valente, Mauro Andrés Malano, Francisco Mauricio Pérez, Pedro Antonio
author_facet	Valente, Mauro Andrés Malano, Francisco Mauricio Pérez, Pedro Antonio
author_sort	Valente, Mauro Andrés
title	Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code
title_short	Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code
title_full	Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code
title_fullStr	Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code
title_full_unstemmed	Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code
title_sort	internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the fluka code
publishDate	2014
url	http://hdl.handle.net/11086/20130 https://doi.org/10.22323/1.194.0088
work_keys_str_mv	AT valentemauroandres internaldosimetryforalphaemittersradiopharmaceuticalsinbiologicaltissuestudiedwiththeflukacode AT malanofranciscomauricio internaldosimetryforalphaemittersradiopharmaceuticalsinbiologicaltissuestudiedwiththeflukacode AT perezpedroantonio internaldosimetryforalphaemittersradiopharmaceuticalsinbiologicaltissuestudiedwiththeflukacode
_version_	1756009588897873920

Internal dosimetry for alpha emitters radiopharmaceuticals in biological tissue studied with the FLUKA code

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