A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss

The phytochemical study of the chloroform soluble part of the hydroalcoholic extract of Marrubium deserti allowed us to describe a new labdane diterpene, 6-dehydroxy-19-acetyl marrubenol (3) beside three other diterpenes: 19-acetyl-marrubenol (6), 6-acetyl-marrubenol (7) and 16-epoxy-9-hydroxylabda-13(16), 14- diene (1). This latter derivative is described for the first time as natural compound. Phytol (2), and three sterols: β-sitosterol (4), stigmasterol (5) and β-sitosterol 3-O-glucoside (8) were also isolated from this species. Structure elucidation of the isolated compounds was accomplished by means of spectroscopic techniques, especially NMR spectroscopy and mass spectrometry.

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Bibliographic Details
Main Authors: Dendougui, Hocine, Seghir, Souad, Belloum, Zahia, Benayache, Fadila, León, Francisco, Brouard, Ignacio, Bermejo, Jaime, Benayache, Samir
Other Authors: Ministère de l'Enseignement Supérieur et de la Recherche Scientifique (Algerie)
Format: artículo biblioteca
Published: ACG Publications 2011-04-15
Subjects:Lamiaceae, Marrubium deserti, Diterpenoids, Sterols, Phytol,
Online Access:http://hdl.handle.net/10261/199650
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spelling dig-ipna-es-10261-1996502024-05-13T10:44:28Z A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss Dendougui, Hocine Seghir, Souad Belloum, Zahia Benayache, Fadila León, Francisco Brouard, Ignacio Bermejo, Jaime Benayache, Samir Ministère de l'Enseignement Supérieur et de la Recherche Scientifique (Algerie) Lamiaceae Marrubium deserti Diterpenoids Sterols Phytol The phytochemical study of the chloroform soluble part of the hydroalcoholic extract of Marrubium deserti allowed us to describe a new labdane diterpene, 6-dehydroxy-19-acetyl marrubenol (3) beside three other diterpenes: 19-acetyl-marrubenol (6), 6-acetyl-marrubenol (7) and 16-epoxy-9-hydroxylabda-13(16), 14- diene (1). This latter derivative is described for the first time as natural compound. Phytol (2), and three sterols: β-sitosterol (4), stigmasterol (5) and β-sitosterol 3-O-glucoside (8) were also isolated from this species. Structure elucidation of the isolated compounds was accomplished by means of spectroscopic techniques, especially NMR spectroscopy and mass spectrometry. This research was supported by FNR program of Algerian Ministry of research and PCI program of cooperation between Algeria and Spain. 2020-02-04T12:28:42Z 2020-02-04T12:28:42Z 2011-04-15 2020-02-04T12:28:43Z artículo http://purl.org/coar/resource_type/c_6501 issn: 1307-6167 Records of Natural Products 5(4): 300-304 (2011) http://hdl.handle.net/10261/199650 Publisher's version https://acgpubs.org/doc/2018080617051538-RNP-1007-263.pdf Sí open ACG Publications
institution IPNA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-ipna-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IPNA España
topic Lamiaceae
Marrubium deserti
Diterpenoids
Sterols
Phytol
Lamiaceae
Marrubium deserti
Diterpenoids
Sterols
Phytol
spellingShingle Lamiaceae
Marrubium deserti
Diterpenoids
Sterols
Phytol
Lamiaceae
Marrubium deserti
Diterpenoids
Sterols
Phytol
Dendougui, Hocine
Seghir, Souad
Belloum, Zahia
Benayache, Fadila
León, Francisco
Brouard, Ignacio
Bermejo, Jaime
Benayache, Samir
A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss
description The phytochemical study of the chloroform soluble part of the hydroalcoholic extract of Marrubium deserti allowed us to describe a new labdane diterpene, 6-dehydroxy-19-acetyl marrubenol (3) beside three other diterpenes: 19-acetyl-marrubenol (6), 6-acetyl-marrubenol (7) and 16-epoxy-9-hydroxylabda-13(16), 14- diene (1). This latter derivative is described for the first time as natural compound. Phytol (2), and three sterols: β-sitosterol (4), stigmasterol (5) and β-sitosterol 3-O-glucoside (8) were also isolated from this species. Structure elucidation of the isolated compounds was accomplished by means of spectroscopic techniques, especially NMR spectroscopy and mass spectrometry.
author2 Ministère de l'Enseignement Supérieur et de la Recherche Scientifique (Algerie)
author_facet Ministère de l'Enseignement Supérieur et de la Recherche Scientifique (Algerie)
Dendougui, Hocine
Seghir, Souad
Belloum, Zahia
Benayache, Fadila
León, Francisco
Brouard, Ignacio
Bermejo, Jaime
Benayache, Samir
format artículo
topic_facet Lamiaceae
Marrubium deserti
Diterpenoids
Sterols
Phytol
author Dendougui, Hocine
Seghir, Souad
Belloum, Zahia
Benayache, Fadila
León, Francisco
Brouard, Ignacio
Bermejo, Jaime
Benayache, Samir
author_sort Dendougui, Hocine
title A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss
title_short A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss
title_full A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss
title_fullStr A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss
title_full_unstemmed A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss
title_sort new labdane diterpene and other constituents from marrubium deserti noe ex coss
publisher ACG Publications
publishDate 2011-04-15
url http://hdl.handle.net/10261/199650
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