Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives
4 pages, 1 figure, 1 table, 2 schemes.
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Bentham Science Publishers
2005-11
|
| Subjects: | Antineoplastic agents, Breast cancer, Pyrroles, Diversity-oriented synthesis, Tyrosine kinase inhibitors, Silica gel, SU11248, |
| Online Access: | http://hdl.handle.net/10261/13463 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dig-ipna-es-10261-13463 |
|---|---|
| record_format |
koha |
| spelling |
dig-ipna-es-10261-134632019-11-12T14:22:15Z Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives Padrón, José M. Tejedor, David Santos-Expósito, Alicia García-Tellado, Fernando Villar, Jesús Martín, Víctor S. Ministerio de Educación y Ciencia (España) Gobierno de Canarias Instituto Canario de Investigación del Cáncer Antineoplastic agents Breast cancer Pyrroles Diversity-oriented synthesis Tyrosine kinase inhibitors Silica gel SU11248 4 pages, 1 figure, 1 table, 2 schemes. A series of tetrasubstituted pyrrole derivatives, structurally related to tyrosine kinase inhibitors, has been synthesized one-pot by irradiation of a silica gel absorbed mixture of a conjugated alkynoate and a primary amine. The compounds were evaluated for their anticancer activities using the human breast cancer cell lines T-47D and MCF7. This research was supported by grants PPQ2002-04361-C04-02 and PPQ2002-04361-C04-03 from the Spanish MEC and the Canary Islands Government. We are grateful to ICIC, for the award of postdoctoral research fellowships to J.M.P. and D.T. F.G.T. also thanks ICIC for financial support (ISCiii, RTICCC C03/10). 2009-06-04T08:43:44Z 2009-06-04T08:43:44Z 2005-11 artículo http://purl.org/coar/resource_type/c_6501 Letters in Drug Design & Discovery 2(7): 529-532 (2005) 1570-1808 http://hdl.handle.net/10261/13463 en http://www.bentham.org/lddd/contabs/lddd2-7.htm none 2373 bytes 1230166 bytes text/plain application/pdf Bentham Science Publishers |
| institution |
IPNA ES |
| collection |
DSpace |
| country |
España |
| countrycode |
ES |
| component |
Bibliográfico |
| access |
En linea |
| databasecode |
dig-ipna-es |
| tag |
biblioteca |
| region |
Europa del Sur |
| libraryname |
Biblioteca del IPNA España |
| language |
English |
| topic |
Antineoplastic agents Breast cancer Pyrroles Diversity-oriented synthesis Tyrosine kinase inhibitors Silica gel SU11248 Antineoplastic agents Breast cancer Pyrroles Diversity-oriented synthesis Tyrosine kinase inhibitors Silica gel SU11248 |
| spellingShingle |
Antineoplastic agents Breast cancer Pyrroles Diversity-oriented synthesis Tyrosine kinase inhibitors Silica gel SU11248 Antineoplastic agents Breast cancer Pyrroles Diversity-oriented synthesis Tyrosine kinase inhibitors Silica gel SU11248 Padrón, José M. Tejedor, David Santos-Expósito, Alicia García-Tellado, Fernando Villar, Jesús Martín, Víctor S. Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| description |
4 pages, 1 figure, 1 table, 2 schemes. |
| author2 |
Ministerio de Educación y Ciencia (España) |
| author_facet |
Ministerio de Educación y Ciencia (España) Padrón, José M. Tejedor, David Santos-Expósito, Alicia García-Tellado, Fernando Villar, Jesús Martín, Víctor S. |
| format |
artículo |
| topic_facet |
Antineoplastic agents Breast cancer Pyrroles Diversity-oriented synthesis Tyrosine kinase inhibitors Silica gel SU11248 |
| author |
Padrón, José M. Tejedor, David Santos-Expósito, Alicia García-Tellado, Fernando Villar, Jesús Martín, Víctor S. |
| author_sort |
Padrón, José M. |
| title |
Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| title_short |
Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| title_full |
Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| title_fullStr |
Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| title_full_unstemmed |
Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| title_sort |
synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives |
| publisher |
Bentham Science Publishers |
| publishDate |
2005-11 |
| url |
http://hdl.handle.net/10261/13463 |
| work_keys_str_mv |
AT padronjosem synthesisandantibreastcanceractivityoftetrasubstitutedpyrrolederivatives AT tejedordavid synthesisandantibreastcanceractivityoftetrasubstitutedpyrrolederivatives AT santosexpositoalicia synthesisandantibreastcanceractivityoftetrasubstitutedpyrrolederivatives AT garciatelladofernando synthesisandantibreastcanceractivityoftetrasubstitutedpyrrolederivatives AT villarjesus synthesisandantibreastcanceractivityoftetrasubstitutedpyrrolederivatives AT martinvictors synthesisandantibreastcanceractivityoftetrasubstitutedpyrrolederivatives |
| _version_ |
1777669627935981568 |