MEK signalling pathway is required for hypoblast specification and migration in ovine

MEK signalling pathway is required for hypoblast specification and migration in ovine

MEK signalling pathway is required for hypoblast differentiation in mouse embryos, but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is required for hypoblast specification in the inner cell mass of the ovine blastocyst and that it plays a role during the hypoblast migration occurring following blastocyst hatching.

Saved in:
Bibliographic Details
Main Authors: Martínez de Los Reyes, Nuria, Flores-Borobia, Inés, Carvajal-Serna, Melissa, Marigorta, Pilar, Bermejo Álvarez, Pablo, Ramos Ibeas, Priscila
Other Authors: Martínez de Los Reyes, Nuria [0009-0009-1578-5537]
Format: artículo biblioteca
Language:English
Published: BioScientífica 2024-04-29
Online Access:http://hdl.handle.net/10261/358267
https://api.elsevier.com/content/abstract/scopus_id/85191700511
Tags: Add Tag
No Tags, Be the first to tag this record!
id dig-inia-es-10261-358267
record_format koha
spelling dig-inia-es-10261-3582672024-05-24T20:36:39Z MEK signalling pathway is required for hypoblast specification and migration in ovine Martínez de Los Reyes, Nuria Flores-Borobia, Inés Carvajal-Serna, Melissa Marigorta, Pilar Bermejo Álvarez, Pablo Ramos Ibeas, Priscila Martínez de Los Reyes, Nuria [0009-0009-1578-5537] Flores-Borobia, Inés [0009-0001-1551-0439] Carvajal-Serna, Melissa [0000-0003-3929-5064] Marigorta, Pilar [0000-0002-6287-5780] Bermejo Álvarez, Pablo [0000-0001-9907-2626] Ramos Ibeas, Priscila [0000-0003-4578-0189] MEK signalling pathway is required for hypoblast differentiation in mouse embryos, but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is required for hypoblast specification in the inner cell mass of the ovine blastocyst and that it plays a role during the hypoblast migration occurring following blastocyst hatching. Peer reviewed 2024-05-24T06:31:34Z 2024-05-24T06:31:34Z 2024-04-29 artículo Reproduction 167(6): e240003 (2024) 1470-1626 http://hdl.handle.net/10261/358267 10.1530/REP-24-0003 1741-7899 38552319 2-s2.0-85191700511 https://api.elsevier.com/content/abstract/scopus_id/85191700511 en Departamento de Reproducción Animal​  Publisher's version https://doi.org/10.1530/REP-24-0003 Sí open BioScientífica
institution INIA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-inia-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del INIA España
language English
description MEK signalling pathway is required for hypoblast differentiation in mouse embryos, but its role in ungulate embryos remains controversial. This paper demonstrates that MEK is required for hypoblast specification in the inner cell mass of the ovine blastocyst and that it plays a role during the hypoblast migration occurring following blastocyst hatching.
author2 Martínez de Los Reyes, Nuria [0009-0009-1578-5537]
author_facet Martínez de Los Reyes, Nuria [0009-0009-1578-5537]
Martínez de Los Reyes, Nuria
Flores-Borobia, Inés
Carvajal-Serna, Melissa
Marigorta, Pilar
Bermejo Álvarez, Pablo
Ramos Ibeas, Priscila
format artículo
author Martínez de Los Reyes, Nuria
Flores-Borobia, Inés
Carvajal-Serna, Melissa
Marigorta, Pilar
Bermejo Álvarez, Pablo
Ramos Ibeas, Priscila
spellingShingle Martínez de Los Reyes, Nuria
Flores-Borobia, Inés
Carvajal-Serna, Melissa
Marigorta, Pilar
Bermejo Álvarez, Pablo
Ramos Ibeas, Priscila
MEK signalling pathway is required for hypoblast specification and migration in ovine
author_sort Martínez de Los Reyes, Nuria
title MEK signalling pathway is required for hypoblast specification and migration in ovine
title_short MEK signalling pathway is required for hypoblast specification and migration in ovine
title_full MEK signalling pathway is required for hypoblast specification and migration in ovine
title_fullStr MEK signalling pathway is required for hypoblast specification and migration in ovine
title_full_unstemmed MEK signalling pathway is required for hypoblast specification and migration in ovine
title_sort mek signalling pathway is required for hypoblast specification and migration in ovine
publisher BioScientífica
publishDate 2024-04-29
url http://hdl.handle.net/10261/358267
https://api.elsevier.com/content/abstract/scopus_id/85191700511
work_keys_str_mv AT martinezdelosreyesnuria meksignallingpathwayisrequiredforhypoblastspecificationandmigrationinovine
AT floresborobiaines meksignallingpathwayisrequiredforhypoblastspecificationandmigrationinovine
AT carvajalsernamelissa meksignallingpathwayisrequiredforhypoblastspecificationandmigrationinovine
AT marigortapilar meksignallingpathwayisrequiredforhypoblastspecificationandmigrationinovine
AT bermejoalvarezpablo meksignallingpathwayisrequiredforhypoblastspecificationandmigrationinovine
AT ramosibeaspriscila meksignallingpathwayisrequiredforhypoblastspecificationandmigrationinovine
_version_ 1802819947289640960

Similar Items