Mushrooms as a source of anti-inflammatory agents
Inflammation is nowadays well known to be involved in the development of several chronic diseases such as arteriosclerosis, obesity, diabetes, neurodegenerative diseases, and cancer. Treatment for chronic inflammatory disorders has not been solved yet, and there is an urgent need to find new and safe anti-inflammatory preventive and therapeutic compounds. Medicinal mushrooms have been traditionally used in Asian countries to manage and treat different diseases. On the other hand, edible mushrooms have recently attracted much interest as a functional food because of their antimutagenic, anti-tumoral, anti-viral, anti-thrombotic, hypocholesterolemic, hypolipidemic, and anti-oxidant properties. Among all of these healthy properties, special attention was paid to the immunomodulatory activity of some fungal compounds such as polysaccharides, mainly β-glucans. Recently, some studies have demonstrated that both whole mushrooms and extracts may show anti-inflammatory activity due to the presence of bioactive compounds. This review summarizes the most recent studies investigating immunomodulatory and especially, anti-inflammatory properties of both medicinal and edible mushrooms, the compounds putatively implicated and the mechanisms that were already established. © 2010 Bentham Science Publishers Ltd.
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Format: | artículo biblioteca |
Language: | English |
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Bentham Science Publishers
2010
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Subjects: | Mushrooms, Anti-inflammatory effect, Antioxidants, Immunomodulatory effect, Polysaccharides, |
Online Access: | http://hdl.handle.net/20.500.12792/1620 http://hdl.handle.net/10261/292710 |
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dig-inia-es-10261-2927102023-02-20T07:31:43Z Mushrooms as a source of anti-inflammatory agents García Lafuente, Ana María Moro, C. Villares, A. Guillamón Fernández, Eva Rostagno, M. A. D'Arrigo, M. Martínez, J. A. Mushrooms Anti-inflammatory effect Antioxidants Immunomodulatory effect Polysaccharides Inflammation is nowadays well known to be involved in the development of several chronic diseases such as arteriosclerosis, obesity, diabetes, neurodegenerative diseases, and cancer. Treatment for chronic inflammatory disorders has not been solved yet, and there is an urgent need to find new and safe anti-inflammatory preventive and therapeutic compounds. Medicinal mushrooms have been traditionally used in Asian countries to manage and treat different diseases. On the other hand, edible mushrooms have recently attracted much interest as a functional food because of their antimutagenic, anti-tumoral, anti-viral, anti-thrombotic, hypocholesterolemic, hypolipidemic, and anti-oxidant properties. Among all of these healthy properties, special attention was paid to the immunomodulatory activity of some fungal compounds such as polysaccharides, mainly β-glucans. Recently, some studies have demonstrated that both whole mushrooms and extracts may show anti-inflammatory activity due to the presence of bioactive compounds. This review summarizes the most recent studies investigating immunomodulatory and especially, anti-inflammatory properties of both medicinal and edible mushrooms, the compounds putatively implicated and the mechanisms that were already established. © 2010 Bentham Science Publishers Ltd. 2023-02-20T07:31:43Z 2023-02-20T07:31:43Z 2010 artículo Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry 9(2): 125-141 (2010) 1871-5230 http://hdl.handle.net/20.500.12792/1620 http://hdl.handle.net/10261/292710 10.2174/187152310791110643 1875-614X en none Bentham Science Publishers |
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Mushrooms Anti-inflammatory effect Antioxidants Immunomodulatory effect Polysaccharides Mushrooms Anti-inflammatory effect Antioxidants Immunomodulatory effect Polysaccharides |
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Mushrooms Anti-inflammatory effect Antioxidants Immunomodulatory effect Polysaccharides Mushrooms Anti-inflammatory effect Antioxidants Immunomodulatory effect Polysaccharides García Lafuente, Ana María Moro, C. Villares, A. Guillamón Fernández, Eva Rostagno, M. A. D'Arrigo, M. Martínez, J. A. Mushrooms as a source of anti-inflammatory agents |
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Inflammation is nowadays well known to be involved in the development of several chronic diseases such as arteriosclerosis, obesity, diabetes, neurodegenerative diseases, and cancer. Treatment for chronic inflammatory disorders has not been solved yet, and there is an urgent need to find new and safe anti-inflammatory preventive and therapeutic compounds. Medicinal mushrooms have been traditionally used in Asian countries to manage and treat different diseases. On the other hand, edible mushrooms have recently attracted much interest as a functional food because of their antimutagenic, anti-tumoral, anti-viral, anti-thrombotic, hypocholesterolemic, hypolipidemic, and anti-oxidant properties. Among all of these healthy properties, special attention was paid to the immunomodulatory activity of some fungal compounds such as polysaccharides, mainly β-glucans. Recently, some studies have demonstrated that both whole mushrooms and extracts may show anti-inflammatory activity due to the presence of bioactive compounds. This review summarizes the most recent studies investigating immunomodulatory and especially, anti-inflammatory properties of both medicinal and edible mushrooms, the compounds putatively implicated and the mechanisms that were already established. © 2010 Bentham Science Publishers Ltd. |
format |
artículo |
topic_facet |
Mushrooms Anti-inflammatory effect Antioxidants Immunomodulatory effect Polysaccharides |
author |
García Lafuente, Ana María Moro, C. Villares, A. Guillamón Fernández, Eva Rostagno, M. A. D'Arrigo, M. Martínez, J. A. |
author_facet |
García Lafuente, Ana María Moro, C. Villares, A. Guillamón Fernández, Eva Rostagno, M. A. D'Arrigo, M. Martínez, J. A. |
author_sort |
García Lafuente, Ana María |
title |
Mushrooms as a source of anti-inflammatory agents |
title_short |
Mushrooms as a source of anti-inflammatory agents |
title_full |
Mushrooms as a source of anti-inflammatory agents |
title_fullStr |
Mushrooms as a source of anti-inflammatory agents |
title_full_unstemmed |
Mushrooms as a source of anti-inflammatory agents |
title_sort |
mushrooms as a source of anti-inflammatory agents |
publisher |
Bentham Science Publishers |
publishDate |
2010 |
url |
http://hdl.handle.net/20.500.12792/1620 http://hdl.handle.net/10261/292710 |
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1767603382558654464 |