Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin
Teasing apart the effects of natural selection and demography on current allele frequencies is challenging, due to both processes leaving a similar molecular footprint. In particular, when attempting to identify selection in species that have undergone a recent range expansion, the increase in genetic drift at the edges of range expansions (“allele surfing”) can be a confounding factor. To address this potential issue, we first assess the long-range colonization history of the Aleppo pine across the Mediterranean Basin, using molecular markers. We then look for single nucleotide polymorphisms (SNPs) involved in local adaptation using: (a) environmental correlation methods (bayenv2), focusing on bioclimatic variables important for the species’ adaptation (i.e., temperature, precipitation and water availability); and (b) FST-related methods (pcadapt). To assess the rate of false positives caused by the allele surfing effect, these results are compared with results from simulated SNP data that mimics the species’ past range expansions and the effect of genetic drift, but with no selection. We find that the Aleppo pine shows a previously unsuspected complex genetic structure across its range, as well as evidence of selection acting on SNPs involved with the response to bioclimatic variables such as drought. This study uses an original approach to disentangle the confounding effects of drift and selection in range margin populations. It also contributes to the increased evidence that plant populations are able to adapt to new environments despite the expected accumulation of deleterious mutations that takes place during long-range colonizations.
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Format: | artículo biblioteca |
Language: | English |
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Wiley
2018
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Subjects: | Adaptation, Allele surfing, Environmental association, Genetic differentiation, Outliers, |
Online Access: | http://hdl.handle.net/20.500.12792/749 http://hdl.handle.net/10261/290752 |
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dig-inia-es-10261-2907522023-02-17T12:29:03Z Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin Ruiz Daniels, R. Taylor, R. S. Serra Varela, María Jesús Vendramin, G. G. González-Martínez, S. C. Grivet Delphine, Delphine Adaptation Allele surfing Environmental association Genetic differentiation Outliers Teasing apart the effects of natural selection and demography on current allele frequencies is challenging, due to both processes leaving a similar molecular footprint. In particular, when attempting to identify selection in species that have undergone a recent range expansion, the increase in genetic drift at the edges of range expansions (“allele surfing”) can be a confounding factor. To address this potential issue, we first assess the long-range colonization history of the Aleppo pine across the Mediterranean Basin, using molecular markers. We then look for single nucleotide polymorphisms (SNPs) involved in local adaptation using: (a) environmental correlation methods (bayenv2), focusing on bioclimatic variables important for the species’ adaptation (i.e., temperature, precipitation and water availability); and (b) FST-related methods (pcadapt). To assess the rate of false positives caused by the allele surfing effect, these results are compared with results from simulated SNP data that mimics the species’ past range expansions and the effect of genetic drift, but with no selection. We find that the Aleppo pine shows a previously unsuspected complex genetic structure across its range, as well as evidence of selection acting on SNPs involved with the response to bioclimatic variables such as drought. This study uses an original approach to disentangle the confounding effects of drift and selection in range margin populations. It also contributes to the increased evidence that plant populations are able to adapt to new environments despite the expected accumulation of deleterious mutations that takes place during long-range colonizations. 2023-02-17T12:29:03Z 2023-02-17T12:29:03Z 2018 artículo Molecular Ecology 27: 3331-3345 (2018) 0962-1083 http://hdl.handle.net/20.500.12792/749 http://hdl.handle.net/10261/290752 10.1111/mec.14786 1365-294X en none Wiley |
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Adaptation Allele surfing Environmental association Genetic differentiation Outliers Adaptation Allele surfing Environmental association Genetic differentiation Outliers |
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Adaptation Allele surfing Environmental association Genetic differentiation Outliers Adaptation Allele surfing Environmental association Genetic differentiation Outliers Ruiz Daniels, R. Taylor, R. S. Serra Varela, María Jesús Vendramin, G. G. González-Martínez, S. C. Grivet Delphine, Delphine Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin |
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Teasing apart the effects of natural selection and demography on current allele frequencies is challenging, due to both processes leaving a similar molecular footprint. In particular, when attempting to identify selection in species that have undergone a recent range expansion, the increase in genetic drift at the edges of range expansions (“allele surfing”) can be a confounding factor. To address this potential issue, we first assess the long-range colonization history of the Aleppo pine across the Mediterranean Basin, using molecular markers. We then look for single nucleotide polymorphisms (SNPs) involved in local adaptation using: (a) environmental correlation methods (bayenv2), focusing on bioclimatic variables important for the species’ adaptation (i.e., temperature, precipitation and water availability); and (b) FST-related methods (pcadapt). To assess the rate of false positives caused by the allele surfing effect, these results are compared with results from simulated SNP data that mimics the species’ past range expansions and the effect of genetic drift, but with no selection. We find that the Aleppo pine shows a previously unsuspected complex genetic structure across its range, as well as evidence of selection acting on SNPs involved with the response to bioclimatic variables such as drought. This study uses an original approach to disentangle the confounding effects of drift and selection in range margin populations. It also contributes to the increased evidence that plant populations are able to adapt to new environments despite the expected accumulation of deleterious mutations that takes place during long-range colonizations. |
format |
artículo |
topic_facet |
Adaptation Allele surfing Environmental association Genetic differentiation Outliers |
author |
Ruiz Daniels, R. Taylor, R. S. Serra Varela, María Jesús Vendramin, G. G. González-Martínez, S. C. Grivet Delphine, Delphine |
author_facet |
Ruiz Daniels, R. Taylor, R. S. Serra Varela, María Jesús Vendramin, G. G. González-Martínez, S. C. Grivet Delphine, Delphine |
author_sort |
Ruiz Daniels, R. |
title |
Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin |
title_short |
Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin |
title_full |
Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin |
title_fullStr |
Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin |
title_full_unstemmed |
Inferring selection in instances of long-range colonization The Aleppo pine (Pinus halepensis) in the Mediterranean Basin |
title_sort |
inferring selection in instances of long-range colonization the aleppo pine (pinus halepensis) in the mediterranean basin |
publisher |
Wiley |
publishDate |
2018 |
url |
http://hdl.handle.net/20.500.12792/749 http://hdl.handle.net/10261/290752 |
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