Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep
7 páginas, 2 figuras.
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| Format: | artículo biblioteca |
| Language: | English |
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Elsevier
2013
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| Subjects: | Fusarium, Pathology, Sheep, T-2 toxicosis, |
| Online Access: | http://hdl.handle.net/10261/86652 |
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dig-igm-es-10261-866522021-04-13T15:21:02Z Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep Ferreras, Mª del Carmen Benavides, Julio García Pariente, C. Delgado, L. Fuertes, M. Muñoz, María García Marín, Juan Francisco Pérez Pérez, Valentín Moredun Research Institute Fusarium Pathology Sheep T-2 toxicosis 7 páginas, 2 figuras. A flock of approximately 1,000 sheep were exposed intermittently to food contaminated with T-2 toxin (T-2), a potent type-A trichothecene mycotoxin produced primarily by Fusarium sporotrichioides and Fusarium poae. In the acute stage of the intoxication, affected sheep developed anorexia, decreased water consumption, ruminal atony, soft faeces and apathy. One hundred and ninety of the exposed sheep died. The main gross lesions observed in animals dying during the acute disease were rumenitis and ulcerative abomasitis, depletion of lymphocytes in lymphoid organs, necrosis of the exocrine pancreas, myocarditis and intense oedema of the skin and brain. Sheep developing the chronic stage of disease showed weight loss and reproductive inefficiency and the main pathological features observed in animals dying during this stage were gastrointestinal inflammation, myocardial fibrosis and necrotic and suppurative lesions in the oral cavity. Opportunistic infections (e.g. mycotic mastitis or parasitic pneumonia) were also identified in these animals. Increased serum concentrations of lactate dehydrogenase and creatine kinase were observed, most likely related to heart lesions. T-2 toxins were detected in all samples of the diet of these animals that were analyzed. The changes in the sheep reported here are similar to those described previously in experimental studies. Lesions observed in the present animals suggest an additional cardiotoxic effect of T-2 in sheep. Peer reviewed 2013-11-14T09:46:24Z 2013-11-14T09:46:24Z 2013 artículo http://purl.org/coar/resource_type/c_6501 Journal of Comparative Pathology 148 (2-3): 236-242 (2013) 0021-9975 http://hdl.handle.net/10261/86652 10.1016/j.jcpa.2012.05.016 en http://dx.doi.org/10.1016/j.jcpa.2012.05.016 open Elsevier |
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España |
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ES |
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dig-igm-es |
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biblioteca |
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Europa del Sur |
| libraryname |
Biblioteca del IGM España |
| language |
English |
| topic |
Fusarium Pathology Sheep T-2 toxicosis Fusarium Pathology Sheep T-2 toxicosis |
| spellingShingle |
Fusarium Pathology Sheep T-2 toxicosis Fusarium Pathology Sheep T-2 toxicosis Ferreras, Mª del Carmen Benavides, Julio García Pariente, C. Delgado, L. Fuertes, M. Muñoz, María García Marín, Juan Francisco Pérez Pérez, Valentín Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep |
| description |
7 páginas, 2 figuras. |
| author2 |
Moredun Research Institute |
| author_facet |
Moredun Research Institute Ferreras, Mª del Carmen Benavides, Julio García Pariente, C. Delgado, L. Fuertes, M. Muñoz, María García Marín, Juan Francisco Pérez Pérez, Valentín |
| format |
artículo |
| topic_facet |
Fusarium Pathology Sheep T-2 toxicosis |
| author |
Ferreras, Mª del Carmen Benavides, Julio García Pariente, C. Delgado, L. Fuertes, M. Muñoz, María García Marín, Juan Francisco Pérez Pérez, Valentín |
| author_sort |
Ferreras, Mª del Carmen |
| title |
Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep |
| title_short |
Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep |
| title_full |
Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep |
| title_fullStr |
Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep |
| title_full_unstemmed |
Acute and Chronic Disease Associated with Naturally Occurring T-2 Mycotoxicosis in Sheep |
| title_sort |
acute and chronic disease associated with naturally occurring t-2 mycotoxicosis in sheep |
| publisher |
Elsevier |
| publishDate |
2013 |
| url |
http://hdl.handle.net/10261/86652 |
| work_keys_str_mv |
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