microRNAs and regulation of insect oogenesis
Comunicación oral presentada al 8º Congreso de la Asociacion Ibérica de Endocrinología comparada, celebrado en Madrid, entre los días 5 y 7 de septiembre de 2011.
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2011
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dig-ibe-es-10261-503902018-10-03T07:52:33Z microRNAs and regulation of insect oogenesis Tanaka, Erica D. Herraiz, Alba Piulachs, Maria-Dolors Comunicación oral presentada al 8º Congreso de la Asociacion Ibérica de Endocrinología comparada, celebrado en Madrid, entre los días 5 y 7 de septiembre de 2011. In insects, many aspects of reproduction are under the control of hormones, which regulate the synthesis and uptake of yolk proteins, oocyte growth, cell proliferation, chorion synthesis, and apoptosis in ovarian tissues. But most of the genes that participate in these processes are not directly regulated by hormones, thus being good candidates to be regulated by microRNAs (miRNAs). The discovery of non-coding small RNAs, including miRNAs, deeply changed the knowledge on the control of gene expression. In insects, information about miRNAs is still fragmentary and predominantly focused on Drosophila melanogaster. In this species, the processes studied go from neural development, metamorphosis, growth and development, to oogenesis. Our research aims at unveiling how miRNAs are involved in controlling gene expression in insect oogenesis, taking as a model the cockroach Blattella germanica, a phylogenetically basal species with panoistic ovaries. To this end, we recently obtained a library of small RNAs from B. germanica adult ovaries to identify the miRNAs of this cockroach; then, we used quantitative PCR (qPCR) to study the expression of a selection of them. and we are silencing specific miRNAs in order to unveil their function during oogenesis. Data afforded by these approaches, concerning classical miRNAs and novel miRNA candidates, are changing our views about the regulation of insect oogenesis. Peer Reviewed 2012-05-30T07:55:47Z 2012-05-30T07:55:47Z 2011 2012-05-30T07:55:47Z comunicación de congreso http://purl.org/coar/resource_type/c_5794 http://hdl.handle.net/10261/50390 en none |
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Comunicación oral presentada al 8º Congreso de la Asociacion Ibérica de Endocrinología comparada, celebrado en Madrid, entre los días 5 y 7 de septiembre de 2011. |
format |
comunicación de congreso |
author |
Tanaka, Erica D. Herraiz, Alba Piulachs, Maria-Dolors |
spellingShingle |
Tanaka, Erica D. Herraiz, Alba Piulachs, Maria-Dolors microRNAs and regulation of insect oogenesis |
author_facet |
Tanaka, Erica D. Herraiz, Alba Piulachs, Maria-Dolors |
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Tanaka, Erica D. |
title |
microRNAs and regulation of insect oogenesis |
title_short |
microRNAs and regulation of insect oogenesis |
title_full |
microRNAs and regulation of insect oogenesis |
title_fullStr |
microRNAs and regulation of insect oogenesis |
title_full_unstemmed |
microRNAs and regulation of insect oogenesis |
title_sort |
micrornas and regulation of insect oogenesis |
publishDate |
2011 |
url |
http://hdl.handle.net/10261/50390 |
work_keys_str_mv |
AT tanakaericad micrornasandregulationofinsectoogenesis AT herraizalba micrornasandregulationofinsectoogenesis AT piulachsmariadolors micrornasandregulationofinsectoogenesis |
_version_ |
1777668549731418112 |