Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process
Domestication has had a strong impact on the development of modern societies. We sequenced 200 genomes of the chocolate plant Theobroma cacao L. to show for the first time to our knowledge that a single population, the Criollo population, underwent strong domestication ~3600 years ago (95% CI: 2481–13,806 years ago). We also show that during the process of domestication, there was strong selection for genes involved in the metabolism of the colored protectants anthocyanins and the stimulant theobromine, as well as disease resistance genes. Our analyses show that domesticated populations of T. cacao (Criollo) maintain a higher proportion of high-frequency deleterious mutations. We also show for the first time the negative consequences of the increased accumulation of deleterious mutations during domestication on the fitness of individuals (significant reduction in kilograms of beans per hectare per year as Criollo ancestry increases, as estimated from a GLM, P = 0.000425).
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2018
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dig-catie-11554-89602023-11-16T16:34:19Z Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process Cornejo, Omar E.l. Yee, Muh-Ching Domínguez, Víctor Andrews, Mary Sockell, Alexandra Strandberg, Erika Livingstone Ill, Donald Stack, Conrad Romero, Alberto Umaharan, Pathmanathan Royaert, Stefan Tawari, Nilesh R. Ng, Pauline Gutiérrez, Osman A. Phillips Mora, Wilbert Mochaitis, Keithanne Bustamante, Carlos D. Motamayor, Juan C. Domestication has had a strong impact on the development of modern societies. We sequenced 200 genomes of the chocolate plant Theobroma cacao L. to show for the first time to our knowledge that a single population, the Criollo population, underwent strong domestication ~3600 years ago (95% CI: 2481–13,806 years ago). We also show that during the process of domestication, there was strong selection for genes involved in the metabolism of the colored protectants anthocyanins and the stimulant theobromine, as well as disease resistance genes. Our analyses show that domesticated populations of T. cacao (Criollo) maintain a higher proportion of high-frequency deleterious mutations. We also show for the first time the negative consequences of the increased accumulation of deleterious mutations during domestication on the fitness of individuals (significant reduction in kilograms of beans per hectare per year as Criollo ancestry increases, as estimated from a GLM, P = 0.000425). 2018-11-02T14:26:09Z 2018-11-02T14:26:09Z 2018 Artículo https://repositorio.catie.ac.cr/handle/11554/8960 en Communications Biology info:eu-repo/semantics/openAccess application/pdf |
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Domestication has had a strong impact on the development of modern societies. We
sequenced 200 genomes of the chocolate plant Theobroma cacao L. to show for the first time
to our knowledge that a single population, the Criollo population, underwent strong
domestication ~3600 years ago (95% CI: 2481–13,806 years ago). We also show that during
the process of domestication, there was strong selection for genes involved in the metabolism
of the colored protectants anthocyanins and the stimulant theobromine, as well as
disease resistance genes. Our analyses show that domesticated populations of T. cacao
(Criollo) maintain a higher proportion of high-frequency deleterious mutations. We also show
for the first time the negative consequences of the increased accumulation of deleterious
mutations during domestication on the fitness of individuals (significant reduction in kilograms
of beans per hectare per year as Criollo ancestry increases, as estimated from a GLM,
P = 0.000425). |
format |
Artículo |
author |
Cornejo, Omar E.l. Yee, Muh-Ching Domínguez, Víctor Andrews, Mary Sockell, Alexandra Strandberg, Erika Livingstone Ill, Donald Stack, Conrad Romero, Alberto Umaharan, Pathmanathan Royaert, Stefan Tawari, Nilesh R. Ng, Pauline Gutiérrez, Osman A. Phillips Mora, Wilbert Mochaitis, Keithanne Bustamante, Carlos D. Motamayor, Juan C. |
spellingShingle |
Cornejo, Omar E.l. Yee, Muh-Ching Domínguez, Víctor Andrews, Mary Sockell, Alexandra Strandberg, Erika Livingstone Ill, Donald Stack, Conrad Romero, Alberto Umaharan, Pathmanathan Royaert, Stefan Tawari, Nilesh R. Ng, Pauline Gutiérrez, Osman A. Phillips Mora, Wilbert Mochaitis, Keithanne Bustamante, Carlos D. Motamayor, Juan C. Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process |
author_facet |
Cornejo, Omar E.l. Yee, Muh-Ching Domínguez, Víctor Andrews, Mary Sockell, Alexandra Strandberg, Erika Livingstone Ill, Donald Stack, Conrad Romero, Alberto Umaharan, Pathmanathan Royaert, Stefan Tawari, Nilesh R. Ng, Pauline Gutiérrez, Osman A. Phillips Mora, Wilbert Mochaitis, Keithanne Bustamante, Carlos D. Motamayor, Juan C. |
author_sort |
Cornejo, Omar E.l. |
title |
Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process |
title_short |
Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process |
title_full |
Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process |
title_fullStr |
Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process |
title_full_unstemmed |
Population genomic analyses of the chocolate tree, Theobroma cacao L., provide insights into its domestication process |
title_sort |
population genomic analyses of the chocolate tree, theobroma cacao l., provide insights into its domestication process |
publishDate |
2018 |
url |
https://repositorio.catie.ac.cr/handle/11554/8960 |
work_keys_str_mv |
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