Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research [electronic resource] /
1 Xenobiotic Metabolism: From Intact Biosystem to Single Enzymes -- 2 Regulation of Xenobiotic-Metabolizing Cytochromes P450 -- 3 Cytochrome P450 in Human Drug Metabolism: How Much Is Predictable? -- 4 Metabolic Activation of Anticancer Oxazaphosphorines by Cytochrome P450s: Development of a Model for Cancer Gene Therapy -- 5 The Use of Bacteria for Cytochrome P450 Expression -- 6 Expression of Cytochromes P450 in Yeast: Practical Aspects -- 7 Human Cells as an Expression System for Cytochromes P450 -- 8 Metabolic Reactions and Recombinant Isoenzymes of Cytochrome P450: Information Generated and Value for Pharmaceutical Development -- 9 The Importance of Cytochrome P450 3A Enzymes in Drug Metabolism -- 10 Strategies for Verifying the Involvement of Specific Cytochrome P450 Enzymes in Xenobiotic Metabolism -- 11 Regulation of Cytochromes P450 by Substrate Interactions -- 12 Strategies for the Use of Single Cytochrome P450 Enzymes in Drug Research and Future Prospects.
Main Authors: | , , |
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Format: | Texto biblioteca |
Language: | eng |
Published: |
Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,
1994
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Subjects: | Life sciences., Pharmacology., Biochemistry., Life Sciences., Biochemistry, general., Pharmacology/Toxicology., |
Online Access: | http://dx.doi.org/10.1007/978-3-662-03019-6 |
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