Multidisciplinary Approaches to Cholinesterase Functions [electronic resource] /

Impact of Recombinant DNA Technology and Protein Structure Determination on Past and Future Studies on Acetylcholinesterase -- Molecular Polymorphism -- Biosynthesis of the Molecular Forms of Acetylcholinesterase -- Binding of Asymmetric (A12) Acetylcholinesterase to C2 Muscle Cells and to CHO Mutants Defective in Glycosaminoglycan Synthesis -- Subunit Assembly and Glycosylation of Mammalian Brain Acetylcholinesterase -- Molecular Organization of Recombinant Human Acetylcholinesterase -- Expression and Refolding of Functional Human Butyrylcholinesterase from E. coli -- 1: Genetic Variant of Human Acetylcholinesterase - Part 2: SV-40 Transformed Cell Lines, for Example COS-1, but Not Parental Untransformed Cell Lines, Express Butyrylcholinesterase (BCHE) -- Heterogeneity of the Silent Phenotype of Human Butyrylcholinesterase — Identification of Eight New Mutations -- Nematode Acetylcholinesterases: Several Genes and Molecular Forms of their Products -- Drosophila Acetylcholinesterase: Analysis of Structure and Sensitivity to Insecticides by In Vitro Mutagenesis and Expression -- Altered Form of Acetylcholinesterase in Insecticide-Resistant Houseflies (Musca domestica) -- PCR Generated Homologous DNA Probes and Sequence for Acetylcholinesterase Genes in Insect Pests -- Testicular Gene Amplification and Impaired BChE Transcription Induced in Transgenic Mice by the Human BChE Coding Sequence -- Structure Function Relationship -- Three-Dimensional Structure of Acetylcholinesterase -- Sequence Alignment of Esterases and Lipases Based on 3-D Structures of Two Members of This Family -- Structural Analysis of Acetylcholinesterase Ammonium Binding Sites -- Structural Investigations of the Acetylcholinesterase -- Substrate-Selective Inhibition and Peripheral Site Labeling of Acetylcholinesterase by Platinum (Terpyridine) Chloride -- Cryptic Catalysis and Cholinesterase Function -- Influence of Ionic Composition of the Medium on Acetylcholinesterase Conformation -- Molecular Dissection of Functional Domains in Human Cholinesterases Expressed in Microinjected Xenopus Oocytes -- Acetylcholinesterase Catalysis - Protein Engineering Studies -- Site-Directed Mutagenesis of Functional Residues in Torpedo Acetylcholinesterase -- Structurally Important Residues in the Region SER91 to ASN98 of Torpedo Acetylcholinesterase -- A Model of Butyryicholinesterase Based on the X-ray Structure of Acetylcholinesterase Indicates Differences in Specificity -- Molecular Models for Human AChE and its Phosphonylation Products -- Relationships Between Activity of Organophosphorus Inhibitors of Acetylcholinesterase and Accessibility of Phosphorus Atom as Estimated by Molecular Mechanics Calculations -- Physiological Role and Clinical Applications -- Factors Influencing Acetylcholinesterase Regulation in Slow and Fast Skeletal Muscles -- Compartmentalization of Acetylcholinesterase mRNA and Protein Expression in Skeletal Muscle In Vitro and In Vivo: Implications for Regulation at the Neuromuscular Junction -- Towards a Functional Analysis Cholinesterases in Neurogenesis: Histological, Molecular, and Regulatory Features of BChE from Chicken Brain -- Acetylcholinesterase as a Modulatory Neuroprotein and its Influence on Motor Control -- Different Influence of Inhibitors on Acetylcholinesterase Molecular Forms G1 and G4 Isolated from Alzheimer’s Disease and Control Brains -- Acetylcholinesterase Inhibition by Novel Carbamates: A Kinetic and Nuclear Magnetic Resonance Study -- Experimental Acetylcholinesterase Autoimmunity -- Clinical Implications of Cholinesterase Aberrations in Syndromes of Hemopoietic Cell Division -- Acetylcholinesterase: A Pretreatment Drug for Organophosphate Toxicity -- Recommendations for Nomenclature in Cholinesterases.

Bibliographic Details

Main Authors:	Shafferman, Avigdor. editor., Velan, Baruch. editor., SpringerLink (Online service)
Format:	Texto biblioteca
Language:	eng
Published:	Boston, MA : Springer US : Imprint: Springer, 1992
Subjects:	Medicine., Neurosciences., Pharmacology., Biochemistry., Biomedicine., Pharmacology/Toxicology., Biochemistry, general.,
Online Access:	http://dx.doi.org/10.1007/978-1-4615-3046-6
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