Integration of Mitochondrial Function [electronic resource] /

Diffusional Integration of Mitochondrial Function -- Diffusional Integration of Mitochondrial Function: Lateral Diffusion of Proteins in Energy Transduction -- Diffusion and Collision in Cytochrome c-Mediated Electron Transport -- Is Electron Transfer Mediated by Random Diffusion Alone? -- Role of Ubiquinone Diffusion in Mitochondrial Electron Transfer -- Physical Constraints on Lateral Diffusion and Ubiquinone-Mediated Mitochondrial Electron Transport -- Inhibition of Bovine Heart Mitochondrial NADH — Ubiquinone Reductase by Tinopal AN, A Cationic Benzoxazole -- Topographical Changes in Cytochrome C Oxidase in the Soluble and Membrane-Bound Enzyme as Probed by Antibodies to Subunit V and the Whole Enzyme -- Multiple Forms of Cytochrome C Oxidase Observed in Heart Tissue, Myocytes, and Mitochondria by Fourier Transform Infrared Spectroscopy -- Functional Importance of Mitochondrial Cardiolipin in Yeast Cytochrome c Oxidase Activity -- Lateral Diffusion of Mitochondrial F1F0ATP Synthase: A Random Collision Model for Proton Transfer and ATP Synthesis -- Thermodynamic Integration -- Thermodynamics and Control of Proton-Motive Free-Energy Transduction -- The Mechanism of Uncoupling of Oxidative Phosphorylation -- Upper and Lower Limits of Charge, Proton and ATP Stoichiometries of Oxidative Phosphorylation -- ATP/2e? Stoichiometries for the Coupling Sites of Mitochondrial Oxidative Phosphorylation: Evaluation by Equilibrium and Non-Equilibrium Thermodynamics -- Nonequilibrium Thermodynamics and Cellular Bioenergetics -- The Near-Equilibrium Thermodynamics Approach to Living Systems -- The H+/e? Forces and Stoichiometries of the Mitochondrial Respiratory Chain -- Variation of Efficiency with Free Energy Dissipation in Theoretical Models of Oxidative Phosphorylation and Cytochrome Oxidase -- Analysis of Mechanisms of Free Energy Coupling and Uncoupling by Inhibitor Titrations -- Flux Control and Structural Regulation -- Mechanisms Stabilizing the Protonmotive Force in Respiring Mitochondria -- Regulation of Respiration and Pyruvate Dehydrogenase in Isolated Cardiac Myocytes and Hepatocytes -- Control Analysis of Cellular Metabolism: Application to Gluconeogenesis in Rat-Liver Cells -- Mitochondrial Volume Control -- Organization of the Mitochondrial Matrix -- Competition Between Electron Transfer and ATPase in Generating Steady-State Protonmotive Force and Phosphorylation Potential -- Control of Respiration and ATP Hydrolysis in Uncoupled Mitochondria -- Voltage-Dependent Channels are Present in the Inner Membrane of Mitochondria -- The Kinetics of Inorganic Phosphate Uptake and Utilization by Chick Heart Mitochondria -- Possible Role of Membrane-Enzyme Interactions in Activation of Pyruvate Carboxylation and Decarboxylation in Mitochondria -- Duramycin Effects on Mitochondrial Structure and Function -- Mitochondrial Compartmentation of Branched Chain Amino Acid Catabolism: Is the Aminotransferase A Mitochondrial Enzyme? -- Mitochondrial Lactate Dehydrogenase -- Lithium Ion is a Competitive Inhibitor of the Na+ Selective Na+/H+ Antiporter from Mitochondria -- In Situ Assessment of Mitochondrial Function -- Mitochondrial Membrane Potential and pH Gradient in Hypoxic Hepatocytes: Characteristics of the Neahypoxic State -- Blebbing, Cytosolic Free Calcium, and Mitochondrial Membrane Potential Following Toxic and Anoxic Injury in Hepatocytes -- Physiological Significance of a New Adenine Nucleotide Transport Mechanism in Liver Mitochondria -- Integration of Mitochondrial Function with High Aerobic Glycolysis in Tumors: Role of Hexokinase Binding to the Outer Mitochondrial Membrane -- Cytosolic Free Calcium and Myocardial Cell Injury -- Relationships Between Extracellular pH, Intracellular pH, and Cell Injury During ‘Chemical Hypoxia’ -- Regulation of the Mitochondrial ATPase In Situ in Slow and Fast Heart-Rate Hearts -- The Role of Ionized Cytosolic Calcium ([Ca2+]i) in Acute and Chronic Cell Injury -- Succinate and Oxygen Dependence of Mitochondrial Function in Neonatal Hepatocytes -- Cyclic Nucleotides and Mitochondrial Functions at Birth -- Simultaneous Determination of Proton Concentration in Two Compartments -- Tetraphenylphosphonium Ion Distribution in Human Fibroblasts as a Function of In Vitro Aging -- Hormones and Calcium -- The Role of Calcium in the Control of Cell Function -- Hormonal Control of Ca2+-Sensitive Intramitochondrial Enzymes in Mammalian Tissues -- Effect of Mitochondrial Ca++ on Hepatic Aspartate Formation and Gluconeogenic Flux -- Glucagon Stimulation of Mitochondrial Metabolism -- The Function of the Uncoupling Protein in the Intact Brown Fat Cell -- Hormonal Regulation of the Hepatic 2-Oxoglutarate Dehydrogenase Complex -- Ca2+-Dependent NAD(P)+-Induced Alterations in Membrane Permeability of Rat Liver Mitochondria -- Integrated Mitochondrial and Microsomal Regulation of Free Ca2+ in Permeabilized Insulinoma Cells -- The Estimation of the In Vivo Mitochondrial Free Ca2+ Concentration -- Intercellular Integration of Energy-Linked Metabolism -- Metabolic Zonation of Carbohydrate Metabolism in the Liver -- Acinar Compartmentation of Amino Acid and Ammonia Metabolism and Its Functional Significance -- Role of Mitochondria in Zone-Specific Toxicity to the Liver Lobule -- Role of Calcium in Regulation of Hepatic Oxygen Uptake -- Heterogeneity of Energy Metabolism in the Kidney -- Metabolic Key to Hypoxia Tolerance: Loss of Regulatory Links Between the Electron Transfer System and Glycolysis -- Glucagon Actions in Perfused Liver are Oxygen Dependent -- Microzonation of Metabolism Associated with Mitochondrial Distribution in Cells.

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Bibliographic Details
Main Authors: Lemasters, John J. editor., Hackenbrock, Charles R. editor., Thurman, Ronald G. editor., Westerhoff, Hans V. editor., SpringerLink (Online service)
Format: Texto biblioteca
Language:eng
Published: Boston, MA : Springer US : Imprint: Springer, 1988
Subjects:Life sciences., Biochemistry., Cell biology., Cell cycle., Life Sciences., Cell Biology., Cell Cycle Analysis., Animal Biochemistry.,
Online Access:http://dx.doi.org/10.1007/978-1-4899-2551-0
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