Macromolecular Biorecognition [electronic resource] : Principles and Methods /

I. Specific Interactions in Proteins: Molecular Aspects and Functional Regulation -- Computer Graphics as an Aid in Protein Structure-Function Analysis and Design -- Computational Approaches to the Study of Protein-Ligand Interactions -- Synthetic Peptides and the Design of Peptide and Protein Recognition Surfaces -- Limited Proteolysis of Globular Proteins: Molecular Aspects Deduced from Studies on Thermolysin -- Crystallographic Studies on Retinol-Binding Protein and Beta-Lactoglobulin -- Structural Bases for the Recognition of Inhibitors by Serine Proteinases and Their Zymogens -- Role of the Primary Specificity Subsite on the Interaction Between Serine Proteinases and Low Molecular Weight Substrates and Inhibitors -- Interaction Between Serine (pro)Enzymes and Macro-molecular Inhibitors. Thermodynamic and Kinetic Aspects -- Subunit Interactions in Cytochrome Oxidase: The Role of Subunit III -- Myosin Subfragment 1 Catalyzes the Polymerization of Actin at Low Ionic Strength -- Structural Effects in the Self-Association of ?II-Crystallin -- The Role of Lysine-7 in Ribonuclease A -- II. Interaction of Nucleic Acids with Proteins and Drugs -- Transition of Chromatin from the “10 nm” Lower Order Structure to the “30 nm” Higher Order Structure, as Followed by Small Angle X-Ray Scattering -- Topology of DNA in its Interaction with Actinomycin D and with the Histone Octamer -- Thermodynamics and Stereochemistry of the Interaction Between Anthraquinone Drugs and DNA -- Interaction of cis-Ru(DMSO)4Cl2 with DNA in Aqueous Solution -- Studies on the Interaction Between Ribosome and Elongation Factor 2 by Fluorescent Labeling of the Diphthamide Residue -- III. Immunological Recognition and Development of Synthetic Vaccines -- Fine Specificity of Monoclonal Anti-Lysozyme Antibodies and the Three-Dimensional Structure of a Lysozyme-Antibody Complex -- Predicting Antigenicity in Proteins and Future of Synthetic Peptides -- Folding and Antigenicity of Thermolysin Fragments -- Synthesis and Biological Activity of the Immunomodulatory Site of Interleukin 1 -- The 208–222 Region of the Peplomer Glycoprotein as a Putative Binding Site of Rabies Virus with the Nicotinic Acetylcholine Receptor -- Heterogeneity and Specificity of Murine Cell Response to Synthetic Peptide (NANP)n of P. falciparum Circumsporozoite Protein -- Mapping of Antigen Epitopes Interacting with Class II MHC Products and with the Antigen Receptor of T Lymphocytes -- IV. Analytical and Preparative Bioaffinity Methods -- Analytical Use of Antibodies Based on Specific Molecular Binding -- Modified Avidins in Detection Systems -- New Biospecific Chromatographies of ?-Hexosaminidases -- Preparative Applications of Subunit Exchange Chromatography -- Use of Monospecific Antibodies for the Purification of D-Amino Acid Oxidases From Various Sources -- Adsorption of Aromatic Molecules on Hydrophilic Gel Chromatography Media: Effect of Various Salts -- Author Index.

Bibliographic Details

Main Authors:	Chaiken, Irwin. editor., Chiancone, Emilia. editor., Fontana, Angelo. editor., Neri, Paolo. editor., SpringerLink (Online service)
Format:	Texto biblioteca
Language:	eng
Published:	Totowa, NJ : Humana Press, 1987
Subjects:	Life sciences., Biochemistry., Life Sciences., Biochemistry, general.,
Online Access:	http://dx.doi.org/10.1007/978-1-4612-4600-8
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